7:33 AM 7/23/2020 - Hypothesis: The pathogens causing the Disease X-19 circulated in the major local epicenters areas for years (10-15) before the first clinical cases were detected and identified. Besides Sars-Cov-2, they may include, hypothetically, the pathogens of the Hantaviruses Infections, African Swine Fever, and/or other infections, with or without the genomic modifications of these pathogens in a Lab.

11 mysteries about the coronavirus and COVID-19 we have yet to ...


_______________________________________________________________

Blogs from Michael_Novakhov (23 sites) 
Tweets And News - From Michael Novakhov: 7:18 AM 7/23/2020 - The Hypothesis of the Disease X-19
Covid-19-Review: 6:27 AM 7/23/2020 - Study of Covid-19 in Lombardy, Northern Italy "revealed that a sustained community transmission was ongoing way before the first COVID-19 case found in Lombardy."
Covid-19-Review: 10:51 AM 7/22/2020 - "American Triumph" - A Telling (teasing) Name? I noticed a string of them lately, attached to the clusters of Covid-19. Are these the (Russian Mafia) communications? - M.N.
Covid-19-Review: 9:42 AM 7/22/2020 - What We Know and Still Dont Know About COVID-19
Covid-19-Review: 7:01 AM 7/22/2020 - Does this mean that Mouse is the much more likely intermediary host than Bats and Pangolins?
Covid-19-Review: Schumer says Trump should not take the podium at coronavirus briefings: Hes a threat to public health
Covid-19-Review: 11:08 AM 7/21/2020
Tweets And News - From Michael Novakhov: 9:27 AM 7/21/2020 - Army surges past 7000 coronavirus cases as military tops 21000 positive tests
Covid-19-Review: 8:49 AM 7/21/2020
The FBI News Review: 6:54 AM 7/21/2020 - Genomic fingerprinting of covid-19 - GS | Russia's COVID-19 strain did not come from China
Tweets And News - From Michael Novakhov: 1:48 PM 7/20/2020 - Michael Novakhov - SharedNewsLinks: Russia's COVID-19 strain did not come from China
Tweets And News - From Michael Novakhov: Nancy Pelosi warns Trump: Hell be leaving whether he likes it or not
Covid-19-Review: 11:20 AM 7/20/2020 - Michael Novakhov - SharedNewsLinks
The FBI News Review: 10:22 AM 7/20/2020 - We are in the middle of the Biological, Information, Cyber, and Economic Warfare with the Almost Invisible Enemy. It has to be admitted and dealt with as such. Regardless of the status of the Sars-Cov-2, natural or lab-man made, the Pandemic of the Disease X-19 is in itself an act of the BioInfoWar.
The FBI News Review: 8:19 AM 7/20/2020 - Disease X-19 and Security Review: Three new cases of coronavirus have surfaced at U.S. military bases in Japan, two on Okinawa and one in western Tokyo...
Covid-19-Review: 7:56 AM 7/20/2020 - Australian researches detect SARS-CoV-2 virus in wastewater from planes and cruise ships
The FBI News Review: 4:23 PM 7/19/2020
The FBI News Review: 12:06 PM 7/19/2020
The FBI News Review: 11:14 AM 7/19/2020
Covid-19-Review: 11:10 AM 7/19/2020
Covid-19-Review: 7:53 AM 7/19/2020 - How did infants get covid-19 in Texas?
____________________________________________________________

  

Mike Nova's Shared NewsLinks Review In 250 Brief Posts
-
» 7:18 AM 7/23/2020 - The Hypothesis of the Disease X-19
23/07/20 07:24 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from Tweets And News - From Michael Novakhov. The Hypothesis of the Disease X-19 7:18 AM 7/23/2020 Michael Novakhov - SharedNewsLinks - Latest Post Michael Novakhov - SharedNewsLinks   6:27 AM 7/23/2020...
» 6:27 AM 7/23/2020 - Study of Covid-19 in Lombardy, Northern Italy "revealed that a sustained community transmission was ongoing way before the first COVID-19 case found in Lombardy."
23/07/20 07:13 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from Covid-19-Review. Study of Covid-19 in Lombardy, Northern Italy " revealed that a sustained community transmission was ongoing way before the first COVID-19 case found in Lombardy." 6:27 AM 7/23/202...
» Italy’s earliest coronavirus strains did not arrive from China, study suggests
23/07/20 06:34 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story . The earliest coronavirus strains circulating in Italy did not come directly from China, according to a new study. Researchers in Milan collected more than 300 blood samples of Covid-19 patients from t...
» Genomic epidemiology of SARS-CoV-2 reveals multiple lineages and early spread of SARS-CoV-2 infections in Lombardy, Italy
23/07/20 06:15 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story . Abstract From February to April, 2020, Lombardy (Italy) was the area who worldwide registered the highest numbers of SARS-CoV-2 infection. By extensively analyzing 346 whole SARS-CoV-2 genomes, we dem...
» Italy’s first coronavirus strains didn’t come from China, study suggests
23/07/20 05:59 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from Euro Weekly News Spain. A NEW study has suggested that the first Covid-19 variants that spread throughout Italy’s Lombardy region were not from China. The non-peer-reviewed paper published on <a...
» Derek Chauvin: Minneapolis police officer fired over George Floyd killing charged with felony tax crimes
22/07/20 15:26 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from The Independent - World. The fired police officer charged with the murder of George Floyd was charged with felony tax crimes on Wednesday.
» Vessel AMERICAN TRIUMPH (Trawler) IMO 7738412, MMSI 366047000
22/07/20 14:37 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story . FleetMon uses cookies to ensure you get the best experience on our website. Learn more Your browser is out of date! It is great that you want to track the seven seas! Unfortunatly your browser is out ...
» 10:51 AM 7/22/2020 - "American Triumph" - A Telling (teasing) Name? I noticed a string of them lately, attached to the clusters of Covid-19. Are these the (Russian Mafia) communications? - M.N.
22/07/20 13:14 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from Covid-19-Review. 10:51 AM 7/22/2020 - "American Triumph" - A Telling (teasing) Name? I noticed a string of them lately, attached to the clusters of Covid-19. Are these the (Russian Mafia) communica...
» 10:51 AM 7/22/2020 - "American Triumph" - A Telling (teasing) Name? I noticed a string of them lately, attached to the clusters of Covid-19. Are these the (Russian Mafia) communications? - M.N.Covid-19-Review: covid-19-review.blogspot.com/2020/07/1051
22/07/20 13:14 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from mikenov on Twitter. 10:51 AM 7/22/2020 - "American Triumph" - A Telling (teasing) Name? I noticed a string of them lately, attached to the clusters of Covid-19. Are these the (Russian Mafia) commun...
» The fact that American Seafoods had put those stricter rules into place makes the source of the new outbreak somewhat of a mystery.A fishing boat docked in Dutch Harbor with 85 COVID-19 cases. Now it’s headed for Seward. alaskapublic.org/2020/07/19/a-f…
22/07/20 13:13 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from mikenov on Twitter. The fact that American Seafoods had put those stricter rules into place makes the source of the new outbreak somewhat of a mystery. A fishing boat docked in Dutch Harbor with 85...
» FOX News: Bob Just: As Antifa, other radicals rail against police, here's an apology to men and women in blue
22/07/20 12:57 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from 1. World from Michael_Novakhov (27 sites). There’s never an excuse for betraying almost a million police officers for the actions of a few –  and certainly not for the action of one. FOX News
» FOX News: Doctor reinfected with COVID-19 — three months after recovering
22/07/20 12:56 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from 1. World from Michael_Novakhov (27 sites). A doctor in Israel has reportedly been reinfected with COVID-19 — three months after her first bout with the coronavirus. FOX News
» FOX News: De Blasio threatens to take Trump administration to court if federal officials come to New York City
22/07/20 12:54 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from 1. World from Michael_Novakhov (27 sites). New York City Mayor Bill de Blasio on Wednesday threatened to take the Trump administration to court, should they send federal officers to the city amid v...
» Radio Free Europe / Radio Liberty: Rallies In Khabarovsk Continue As Protesters Demand Putin's Resignation
22/07/20 12:53 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from 1. World from Michael_Novakhov (27 sites). Hundreds of supporters of the arrested ex-governor of Russia's Far Eastern Khabarovsk Krai region, Sergei Furgal, have rallied for a 12th day. Radio Free ...
» A fishing boat docked in Dutch Harbor with 85 COVID-19 cases. Now it's headed for Seward. - Alaska Public Media
22/07/20 10:47 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from Alaska Public Media. More than two-thirds of the crew of a huge factory fishing vessel docked in the Aleutian fishing port of Dutch Harbor has tested positive for COVID-19, local authorities announ...
» A fishing boat docked in Dutch Harbor with 85 COVID-19 cases. Now it's headed for Seward.
22/07/20 10:36 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from Google Alert - COVID-19 Outbreak In fish and seafood Industry. American Seafoods had more than 100 COVID - 19 cases on its ships. ... a COVID - 19 response team made up of healthcare officials, sea...
» JBS installs "ultraviolet germicidal" ventilation to combat Covid-19 in slaughterhouses — MercoPress
22/07/20 10:33 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from MercoPress. One of the world's largest meatpackers said they have installed ultraviolet air cleaning equipment in some US plants, as pressure mounts on food companies to protect workers amid growin...
» German abattoir scandal puts cooling systems under COVID spotlight - Reuters
22/07/20 10:08 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story . Business News July 17, 2020 / 8:36 AM / 2 days ago German abattoir scandal puts cooling systems under COVID spotlight Caroline Copley 4 Min Read (This July 17 story corrects to show company name in 15...
» German abattoir scandal puts cooling systems under COVID spotlight
22/07/20 10:06 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from Google Alert - pork plants in germany. Germany's largest pork meat factory had to be shut down because of the recent coronavirus disease (COVID-19) outbreak among its employees.
» What We Know and Still Don’t Know About COVID-19
22/07/20 09:34 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from [Untitled]. COVID-19 and Psychiatric Disorders Q : What do we know about COVID-19, depression and psychiatric disorders? A: We know that the pandemic has had a profound effect on the mental health ...
» Vatican cardinal floats COVID conspiracy theory, suggests virus could be biological weapon
22/07/20 08:43 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from Novena. A Vatican cardinal has floated a COVID conspiracy theory, suggesting that the virus could be a biological weapon. – “The great powers are organising world wars, even bacteriological ones” C...
» Google Alert - CoronaVirus as Biological Weapon: Sanjay Subrahmanyam: Will the Covid-19 pandemic prove a turning point in history?
22/07/20 08:42 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from Disease X-19 as the Bio-weapon from Michael_Novakhov (3 sites). ... whether there were any rumors at the time suggesting that these pandemics were the deliberate or unforeseen consequences of biolo...
» 7:01 AM 7/22/2020 - Does this mean that Mouse is the much more likely intermediary host than Bats and Pangolins?
22/07/20 07:17 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from Covid-19-Review. Does this mean that Mouse is the much more likely intermediary host than Bats and Pangolins for Sars-Cov-2? 7:01 AM 7/22/2020 Michael Novakhov - SharedNewsLinks - Latest Post Micha...
» The PRRA insert at the S1/S2 site modulates cellular tropism of SARS-CoV-2 and ACE2 usage by the closely related Bat raTG13 | bioRxiv
22/07/20 06:29 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story . The PRRA insert at the S1/S2 site modulates cellular tropism of SARS-CoV-2 and ACE2 usage by the closely related Bat raTG13 View ORCID Profile Shufeng Liu , Prabhuanand Selvaraj , Christopher Lien , W...
» New study refutes China’s narrative of COVID-19 being a natural animal-to-human transmission, Opinions & Blogs News
22/07/20 06:26 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story . Since the beginning of the coronavirus pandemic, the Chinese Communist Party has desperately tried to convince the world that SARS-CoV-2, the coronavirus responsible for COVID-19, was naturally transm...
» Google Alert - Sars-Cov-2 origins: Italy's earliest coronavirus strains did not arrive from China, study suggests
22/07/20 06:10 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from Disease X-19 Origins from Michael_Novakhov (3 sites). Researchers in Milan collected more than 300 blood samples of Covid-19 patients from the Lombardy region between February and April and traced ...
» Covid-19 came from europe, not china - Google Search
21/07/20 19:03 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story . Stay up to date on results for Covid-19 came from europe, not china .
» Italy’s earliest coronavirus strains did not arrive from China, study suggests
21/07/20 18:35 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story . Perno’s team collected blood samples from 371 patients in 12 provinces across the region. They were randomly chosen from people admitted to hospital with mild, moderate or severe symptoms. About 7 per...
» COVID-19: Why blood clots are a leading cause for coronavirus deaths
21/07/20 17:41 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story . COVID-19 is a respiratory disease. But reports reveal that the new coronavirus is also killing people by ravaging the circulatory system. Blood clotting is one of the severe complications arising from...
» Google Alert - Covid-19 blood clots: COVID-19: Why blood clots are a leading cause for coronavirus deaths
21/07/20 13:16 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from Disease X-19 Symptoms from Michael_Novakhov (16 sites). COVID - 19 is a respiratory disease. But reports reveal that the new coronavirus is also killing people by ravaging the circulatory system. B...
» Google Alert - covid-19 neurological symptoms: Dementia Tied to Olfaction; Preclinical Alzheimer's Trial; Guillain-Barré and COVID-19
21/07/20 13:09 from Mike Nova's Shared Newslinks
Michael_Novakhov shared this story from Disease X-19 Symptoms from Michael_Novakhov (16 sites). ( Neurology ). Adjunctive rotigotine (Neupro), a dopaminergic agonist used in Parkinson's disease , showed no effect on memory and other cogn...

11 mysteries about the coronavirus and COVID-19 we have yet to solve

1 Share
  • Experts continue to study the coronavirus as the number of people it infects and kills rises each day.
  • Scientists are increasingly certain the coronavirus came from bats but aren't sure exactly how it hopped over to humans.
  • Researchers also don't yet know why the virus doesn't cause symptoms in most children or how long people with antibodies might be immune.
  • Visit Business Insider's homepage for more stories.
In the realm of medicine, what you don't know can indeed kill you.
Six months have passed since China reported the first coronavirus cases to the World Health Organization. But evn now, what experts are still trying to understand sometimes seems to outweigh what they can say for certain.
That is little surprise to any infectious-disease researcher: Highly contagious diseases can move through communities much more quickly than the methodical pace of science can produce vital answers.
What we do know is that the coronavirus seems to have emerged in China as early as mid-November and has now reached 188 countries, infected more than 10.4 million people, and killed around 510,000. Population-level studies using new testing could boost case numbers about 10-fold in the US and perhaps elsewhere as well.
As hospitals around the world care for COVID-19 patients with blood clotsstrokes, and long-lasting respiratory failure, scientists are racing to study the coronavirus, spread life-saving information, and combat dangerous misunderstandings.
Here are 11 of the biggest questions surrounding the coronavirus and COVID-19, and why answering each one is critically important.

7:18 AM 7/23/2020 - The Hypothesis of the Disease X-19

1 Share
Coronavirus in China: The most important lessons from China's ...

The Hypothesis of the Disease X-19

7:18 AM 7/23/2020

Michael Novakhov - SharedNewsLinks - Latest Post

Michael Novakhov - SharedNewsLinks 
6:27 AM 7/23/2020 - Study of Covid-19 in Lombardy, Northern Italy "revealed that a sustained community transmission was ongoing way before the first COVID-19 case found in Lombardy."

Michael_Novakhov shared this story from Covid-19-Review.



6:27 AM 7/23/2020

Hypothesis: The pathogens causing the Disease X-19 circulated in the major local epicenters areas for years (10-15) before the first clinical cases were detected and identified. 
Besides Sars-Cov-2, they may include, hypothetically, the pathogens of the Hantaviruses Infections, African Swine Fever, and/or other infections, with or without the genomic modifications of these pathogens in a Lab. 
The vectors may include pigs, especially industrially produced, as in the Northern areas of Italy and Spain, and various rodents: rats and mice, including the large water or river rats, such as nutrias or coypus. The unusual and very noticeable proliferation of these rodents, especially the large ones, which appear to be sick, infected, and psychotic, was observed in all mayor cities of the world. Quite often, these infections may occur in humans and animals asymptomatically. 

_________________________________________________________________________

Michael Novakhov - SharedNewsLinks 
Italys earliest coronavirus strains did not arrive from China, study suggests

Michael_Novakhov shared this story .

The earliest coronavirus strains circulating in Italy did not come directly from China, according to a new study.
Researchers in Milan collected more than 300 blood samples of Covid-19 patients from the Lombardy region between February and April and traced the origin of the viral strains by changes in their genes.
______________________________________________________



Michael Novakhov - SharedNewsLinks℠ | InBrief | 

Michael Novakhov - SharedNewsLinks 
6:27 AM 7/23/2020 - Study of Covid-19 in Lombardy, Northern Italy "revealed that a sustained community transmission was ongoing way before the first COVID-19 case found in Lombardy."
Italys earliest coronavirus strains did not arrive from China, study suggests
Genomic epidemiology of SARS-CoV-2 reveals multiple lineages and early spread of SARS-CoV-2 infections in Lombardy, Italy
Italys first coronavirus strains didnt come from China, study suggests
Derek Chauvin: Minneapolis police officer fired over George Floyd killing charged with felony tax crimes
Vessel AMERICAN TRIUMPH (Trawler) IMO 7738412, MMSI 366047000
10:51 AM 7/22/2020 - "American Triumph" - A Telling (teasing) Name? I noticed a string of them lately, attached to the clusters of Covid-19. Are these the (Russian Mafia) communications? - M.N.
10:51 AM 7/22/2020 - "American Triumph" - A Telling (teasing) Name? I noticed a string of them lately, attached to the clusters of Covid-19. Are these the (Russian Mafia) communications? - M.N. Covid-19-Review: covid-19-review.blogspot.com/2020/07/1051-a
The fact that American Seafoods had put those stricter rules into place makes the source of the new outbreak somewhat of a mystery. A fishing boat docked in Dutch Harbor with 85 COVID-19 cases. Now its headed for Seward. alaskapublic.org/2020/07/19/a-f via @AKPublicNews
FOX News: Bob Just: As Antifa, other radicals rail against police, here's an apology to men and women in blue
FOX News: Doctor reinfected with COVID-19 three months after recovering
FOX News: De Blasio threatens to take Trump administration to court if federal officials come to New York City
Radio Free Europe / Radio Liberty: Rallies In Khabarovsk Continue As Protesters Demand Putin's Resignation
A fishing boat docked in Dutch Harbor with 85 COVID-19 cases. Now it's headed for Seward. - Alaska Public Media
A fishing boat docked in Dutch Harbor with 85 COVID-19 cases. Now it's headed for Seward.
JBS installs "ultraviolet germicidal" ventilation to combat Covid-19 in slaughterhouses MercoPress
German abattoir scandal puts cooling systems under COVID spotlight - Reuters
German abattoir scandal puts cooling systems under COVID spotlight
What We Know and Still Dont Know About COVID-19
Vatican cardinal floats COVID conspiracy theory, suggests virus could be biological weapon
Google Alert - CoronaVirus as Biological Weapon: Sanjay Subrahmanyam: Will the Covid-19 pandemic prove a turning point in history?
7:01 AM 7/22/2020 - Does this mean that Mouse is the much more likely intermediary host than Bats and Pangolins?
The PRRA insert at the S1/S2 site modulates cellular tropism of SARS-CoV-2 and ACE2 usage by the closely related Bat raTG13 | bioRxiv
New study refutes Chinas narrative of COVID-19 being a natural animal-to-human transmission, Opinions & Blogs News
Google Alert - Sars-Cov-2 origins: Italy's earliest coronavirus strains did not arrive from China, study suggests
_____________________________________________________
Read the whole story

· · · · · · ·

6:27 AM 7/23/2020 - Study of Covid-19 in Lombardy, Northern Italy "revealed that a sustained community transmission was ongoing way before the first COVID-19 case found in Lombardy."

1 Share


Study of Covid-19 in Lombardy, Northern Italy "revealed that a sustained community transmission was ongoing way before the first COVID-19 case found in Lombardy."

6:27 AM 7/23/2020

Hypothesis: The pathogens causing the Disease X-19 circulated in the major local epicenters areas for years (10-15) before the first clinical cases were detected and identified. 
Besides Sars-Cov-2, they may include, hypothetically, the pathogens of the Hantaviruses Infections, African Swine Fever, and/or other infections, with or without the genomic modifications of these pathogens in a Lab. 
The vectors may include pigs, especially industrially produced, as in the Northern areas of Italy and Spain, and various rodents: rats and mice, including the large water or river rats, such as nutrias or coypus. The unusual and very noticeable proliferation of these rodents, especially the large ones, which appear to be sick, infected, and psychotic, was observed in all mayor cities of the world. Quite often, these infections may occur in humans and animals asymptomatically. 

_________________________________________________________________________




Michael Novakhov - SharedNewsLinks 
Italys earliest coronavirus strains did not arrive from China, study suggests

Michael_Novakhov shared this story .

The earliest coronavirus strains circulating in Italy did not come directly from China, according to a new study.
Researchers in Milan collected more than 300 blood samples of Covid-19 patients from the Lombardy region between February and April and traced the origin of the viral strains by changes in their genes.
Read the whole story

· · · ·

Italy’s earliest coronavirus strains did not arrive from China, study suggests

1 Share
The earliest coronavirus strains circulating in Italy did not come directly from China, according to a new study.
Researchers in Milan collected more than 300 blood samples of Covid-19 patients from the Lombardy region between February and April and traced the origin of the viral strains by changes in their genes.

Hong Kong’s biggest mall shocks tenants with lease renewal terms

Italy was the first country in the world that put up a travel restriction barring all flights from China, but the genome sequencing suggested “a transmission chain not directly involving China”, said the researchers led by Professor Carlo Federico Perno of Milan University in a non-peer-reviewed paper posted on <a href="http://medRxiv.org" rel="nofollow">medRxiv.org</a> on Monday.
Get the latest insights and analysis from our Global Impact newsletter on the big stories originating in China.
Lombardy had the earliest known outbreak in the West and has accounted for more than a third of the coronavirus cases in Italy. It is Italy’s richest region with thriving businesses, international transport connections and densely populated urban areas.
Sars-CoV-2, the virus that causes the disease Covid-19, was isolated and sequenced by Chinese researchers in early January. It was not until February 20 that the first case of local infection was confirmed by Lombardy’s health authorities, but “sustained community transmission was ongoing way before” that date, the researchers said.
Perno’s team collected blood samples from 371 patients in 12 provinces across the region. They were randomly chosen from people admitted to hospital with mild, moderate or severe symptoms. About 7 per cent of the samples failed to produce high-quality reading of the virus’ full genome, but the remainder still provided the largest sample base so far from the Lombardy region.

Hong Kong tops previous daily record of 108 Covid-19 cases: sources

The strains belonged to two separate lineages, each playing a dominant role in some provinces. But they “did not contain viral strains isolated in the first months of the outbreak in China”, said the paper.
Italy banned travellers from China on January 31, after a Chinese couple tested positive for Covid-19 in Rome. But according to a study by the Italian National Institute of Health last month, the virus had already appeared in sewage water in Milan and Turin in mid-December.
Perno’s new study showed that there could have been “multiple introductions” of the virus to the Lombardy region. These strains formed relatively isolated clusters in separate areas. One possible direction of the source was Central Europe, where strains with similar mutations had been detected, according to the researchers.
Their calculation suggested that these entries may have happened in the second half of January, based on the assumption that the virus was mutating at a relatively constant speed – although that may not have been the case.
The Italian study is one of several around the world to have found strains that were not traced to China.
In New York, the viral strains circulating in March did not come from China, which researchers said “was unanticipated” because government scientists had gone put extra emphasis on collecting samples in Chinese-speaking neighbourhoods.
“Rather, the sequence analysis suggests probable introductions of Sars-CoV-2 from Europe, from other US locations and local introductions from within New York,” said the official report of the joint research by the city’s Department of Health and the US Centres for Disease Control and Prevention, released last Friday.
A study by the Pasteur Institute in Paris in May confirmed that the outbreak in France had no direct link to China. Another study by Russian government scientists identified 67 introductions into their country and found only one that related to a Chinese source.
Some other studies challenged the belief that the pandemic originated in Wuhan, where the virus was first detected in late December.
A research team led by Spain’s top biologists identified the virus in a waste water sample in Barcelona dated back to March last year. In the Brazilian beach town Florianopolis, drainage samples collected and stored in government research facilities in November later tested positive for the coronavirus.
Benjamin Neuman, professor and chair of biological sciences with the Texas A&M University Texarkana, said that the recent findings could be “potentially a really big story” but that the data would require more scrutiny.
For example, the viral strains detected in sewage samples should have their genome sequenced to determine their position in the evolutionary tree, he said.
“If the sequences are indeed from that early part of the outbreak, it should resemble the earliest sequences from China, possibly with mutations that have not yet been seen,” Professor Neuman said.
They “should not have some of the mutations that appeared later in other parts of the world”, he added.
A government epidemiologist in Beijing, who asked not to be named because they were not authorised to speak to the media, said tracing the origin of the coronavirus by its genes had limitations.
The copies preserved in poor environments such as waste water were probably compromised and unlikely to produce full genome sequences, they said. It would be difficult to estimate a strain’s “age” by mutation because a genetic change appearing later in an international database may not mean it was younger than those sequenced earlier.
“A mutation could be in circulation for some time in a remote corner of the world,” said the researcher. “Can we say that it did not exist until sequencing?”
Purchase the 120+ page China Internet Report 2020 Pro Edition, brought to you by SCMP Research, and enjoy a 30% discount (original price US$400). The report includes deep-dive analysis, trends, and case studies on the 10 most important internet sectors. Now in its 3rd year, this go-to source for understanding China tech also comes with exclusive access to 6+ webinars with C-level executives, including Charles Li, CEO of HKEX, James Peng, CEO/founder of Pony.ai, and senior executives from Alibaba, Huawei, Kuaishou, Pinduoduo, and more. Offer valid until 31 August 2020. To purchase, please click here.
More from South China Morning Post:
For the latest news from the South China Morning Post download our mobile app. Copyright 2020.
Read the whole story

· · · · ·

Genomic epidemiology of SARS-CoV-2 reveals multiple lineages and early spread of SARS-CoV-2 infections in Lombardy, Italy

1 Share

Abstract

From February to April, 2020, Lombardy (Italy) was the area who worldwide registered the highest numbers of SARS-CoV-2 infection. By extensively analyzing 346 whole SARS-CoV-2 genomes, we demonstrated the simultaneous circulation in Lombardy of two major viral lineages, likely derived from multiple introductions, occurring since the second half of January. Seven single nucleotide polymorphisms (five of them non-synonymous) characterized the SARS-CoV-2 sequences, none of them affecting N-glycosylation sites. These two lineages, and the presence of two well defined clusters inside Lineage 1, revealed that a sustained community transmission was ongoing way before the first COVID-19 case found in Lombardy.

Competing Interest Statement

The authors have declared no competing interest.

Funding Statement

This work was financially supported by an unrestricted grant from Cariplo foundation.

Author Declarations

I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
Yes
The details of the IRB/oversight body that provided approval or exemption for the research described are given below:
The study protocol was approved by local Research Ethics Committee of the two hospitals (prot. 92-15032020 and P_20200029440). This study was conducted in accordance with the principles of the 1964 Declaration of Helsinki.
All necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived.
Yes
I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).
Yes
I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable.
Yes

Data Availability

Corresponding author is Carlo Federico Perno, MD, PhD, University of Milan, email: <a href="mailto:cf.perno@uniroma2.it">cf.perno@uniroma2.it</a>. The data that support the findings of this study are available from the corresponding author upon reasonable request.

Read the whole story

· ·

Italy’s first coronavirus strains didn’t come from China, study suggests

1 Share
A NEW study has suggested that the first Covid-19 variants that spread throughout Italy’s Lombardy region were not from China.
The non-peer-reviewed paper published on <a href="http://medRxiv.org" rel="nofollow">medRxiv.org</a> took 371 blood samples of coronavirus patients in Lombardy between February and April and concluded that the Covid-19 strains were ones that had rarely been found in China.
-- Advertisement --
The findings suggest “a transmission chain not directly involving China,” as researchers from Milan University wrote in the study.
Researchers found two different strains in Lombardy, but neither contained “viral strains isolated in the first months of the outbreak in China” suggesting they may have come from Central Europe instead.



Next Page of Stories
Loading...
Page 2

Comments

Popular Posts

8:07 AM 9/5/2020 - Crossfire Hurricane Investigation: It was just a GAS! FBI is dead. The new Service is needed (they are always needed), with the completely different outlooks and mentality than in those present days Pinkertons but without their skills, acumen, and efficiency.

9:30 AM 9/11/2020 - Transverse Myelitis, Possible Adverse Reaction to COVID-19 Vaccine, Explained | Coronavirus Infects, Hijacks Brain - How Does It Work? | How Russia Updated Its Disinformation Playbook for 2020

7:09 AM 9/5/2020 - fbi surveillance Google News: Peter Strzok, Notorious Ex-G-Man, Explains Himself And Takes Aim At Trump

Audio Post - The Tip Of An Iceberg: Sexual Misconduct Within The FBI Is Exposed by AP! Investigate The Investigators who are nothing more and nothing less than a bunch of psychopaths, perverts, and child abusers. Abolish the FBI and put the criminal FBI agents in prison where they belong! The present crisis in America is the direct result of the FBI stupidity, treacherous incompetence and malfeasance.

11:16 AM 4/1/2020 - Look at the Coronavirus map of New York City, it speaks for itself: This is the real Collusion: Trump + Russian Mafia! They conspired to bring to reality the old dream of Trump's: to get rid of the NYC eyesore, its public housing projects, and to build the luxury housing instead, making themselves the tens of billions of bloody $$$.

7:26 AM 9/2/2020 - "That truncated FBI investigation that needs to be resumed immediately." (!!! - M.N.) | There Was No Russia Investigation.

10:06 AM 9/1/2020 - Trump to Visit Kenosha After Sparring with Biden Over Security

5:56 PM 3/29/2020 - Coronavirus Deaths in Germany: Is there a different, less virulent strain of the virus?! Did we do the comparison studies?

8:42 PM 4/1/2020 - Michael Novakhov – SharedNewsLinks℠: Coronavirus Could Spread Through Pipes in Buildings, Officials Fear

8:51 AM 8/30/2020 - "ванька встанька" - ("Teflon effect"): "Putin’s approval rating has jumped to one of its highest levels since February as Russia continues its recovery from the coronavirus outbreak".