Covid-19 Pubmed Articles

Covid-19 Pubmed Articles
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» Checklist for occupational health professionals: Assessing suitability for online interviews using information and communication technology
10/05/25 20:00 from sars-cov-2
OBJECTIVE: Since the outbreak of SARS-CoV-2, there is an increased opportunity for occupational health professionals to conduct online interviews. However, to the best of our knowledge, research regarding adaptation to online interviewin...

» Investigation of trial registration as part of a research integrity assessment of randomised controlled trials in COVID-19 evidence syntheses: a meta-epidemiological study
10/05/25 20:00 from sars-cov-2
CONCLUSIONS: If prospective trial registration is required for inclusion in evidence syntheses, only 6 out of 10 COVID-19 RCTs would be eligible. Restricting eligibility to prospectively registered RCTs would include most large and inter...

» Advances in COVID-19 Therapeutics: Exploring the Role of Lectins and Protease Inhibitors
10/05/25 20:00 from sars-cov-2
The rapid global spread of SARS-CoV-2 has demanded innovative approaches to treatment and prevention. This article reviews the current landscape of COVID-19 therapeutics and vaccines, emphasizing the role of biotechnological products, pa...

» Integration of Student Well-Being in Undergraduate Nursing Curricula: A Scoping Review
10/05/25 20:00 from covid-19
BACKGROUND: Nursing school causes immense stress for students, and the attrition rate is high. Nurse educators have long been aware of the documented relationship between well-being and academic success, as well as the anxiety, depressio...

» Palmitoylated COX-2^Cys555 reprogramed mitochondrial metabolism in pyroptotic inflammatory injury in patients with post-acute COVID-19 syndrome
10/05/25 20:00 from sars-cov-2
CONCLUSION: This study highlights the regulatory role of COX-2^(Cys555) palmitoylation in mitochondrial metabolism and lung inflammatory injury, and suggests potential therapeutic targets to combat respiratory pathogenesis linked to palm...

» Modeling the effects of cross immunity and control measures on competitive dynamics of SARS-CoV-2 variants in the USA, UK, and Brazil
10/05/25 20:00 from sars-cov-2
Mutation in the SARS-CoV-2 virus may lead to the evolution of new variants. The dynamics of these variants varied among countries. Identification of the governing factors responsible for distinctions in their dynamics is important for pr...

» Network modeling of the different SARS-CoV-2 spike protein infection points within the human hematopoietic network
10/05/25 20:00 from sars-cov-2
Hematopoiesis is a physiological process that mainly functions in both the formation and replenishment of varying types of blood cells. SARS-CoV-2 has been reported to affect the human hematopoietic system at multiple infection points le...

» Animal vaccine revolution: Nanoparticle adjuvants open the future of vaccinology
10/05/25 20:00 from sars-cov-2
In recent years, the rapid development of nanoparticle adjuvants has greatly facilitated the treatment and prevention of infectious diseases in humans and animals. The remarkable success of mRNA nanovaccines against SARS-CoV-2 has accele...

» The LDL receptor related protein 1 (LRP1) facilitates ACE2-mediated endocytosis of SARS-CoV2 spike protein-containing pseudovirions
10/05/25 20:00 from sars-cov-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, employs the viral spike (S) protein to associate with host cells. While angiotensin-converting enzyme 2 (ACE2) is a major receptor for the SAR...

» Vanadia Nanozymes Inhibit Platelet Aggregation, Modulate Signaling Pathways and Prevent Pulmonary Embolism in Mice
10/05/25 20:00 from covid-19
Thrombosis is a pathological condition which represents the formation of clots inside blood vessels, blocking the flow of blood through the circulatory system. A high occurrence of thrombotic events, particularly deep vein thrombosis and...

» Uncertainty and decision-making in critical care: lessons from managing COVID-19 ARDS in preparation for the next pandemic
10/05/25 20:00 from coronavirus
CONCLUSION: Future pandemic preparedness programmes should target modifiable influences such as information sharing, teamworking and resource limitations to mitigate against the negative influence of uncertainty and thereby improve decis...

» Symptom Burden and Post-COVID-19 Syndrome 24 Months Following SARS-CoV-2 Infection: Longitudinal Population-Based Study
10/05/25 20:00 from sars-cov-2
CONCLUSIONS: We found a remaining high symptom prevalence two years after SARS-CoV-2 infection, but symptoms present nine months after index infection often resolved, which was associated with increasing hrQoL. Remarkably, a considerable...

» Checklist for occupational health professionals: Assessing suitability for online interviews using information and communication technology
10/05/25 20:00 from covid-19
OBJECTIVE: Since the outbreak of SARS-CoV-2, there is an increased opportunity for occupational health professionals to conduct online interviews. However, to the best of our knowledge, research regarding adaptation to online interviewin...

» Impact of co-infection with SARS-CoV-2 and other respiratory viruses on illness: Pooled analyses of 11 COVID-19 cohorts
10/05/25 20:00 from sars-cov-2
CONCLUSION: In community settings, SARS-CoV-2 co-infection with another virus, particularly HRV, attenuates ARI compared to SARS-CoV-2 single infection. The low number of detected co-infections with other viruses, such as influenza or RS...

» Complete response of musculoskeletal chronic GVHD achieved with extracorporeal photopheresis therapy
10/05/25 20:00 from covid-19
A 48-year-old man with acute myeloid leukemia underwent HLA-matched related donor peripheral blood stem cell transplantation. He developed chronic graft-versus-host disease (cGVHD) of the liver on day 359, which became dependent on cyclo...

» Increase in new-onset type 1 diabetes diagnoses among Brazilian children and adolescents during the COVID-19 pandemic
10/05/25 20:00 from sars-cov-2
CONCLUSIONS: The present findings indicate a significant rise in new T1DM cases among children during the COVID-19 pandemic compared to prior years, without differences in DKA at onset.

» Upadacitinib as monotherapy in patients with rheumatoid arthritis and prior inadequate response to methotrexate: results at 260 weeks from the SELECT-MONOTHERAPY randomised study
10/05/25 20:00 from covid-19
CONCLUSION: No new safety risks were identified with long-term UPA treatment. UPA monotherapy was efficacious in treating rheumatoid arthritis through week 260.

» Consensus Document on COVID-19 from the Spanish Society of Primary Care Physicians (SEMERGEN). Current Situation. SEMERGEN's Position in 2025
10/05/25 20:00 from sars-cov-2
Infection with the SARS-CoV-2 virus is currently one of the most frequent reasons for consultation in Primary Care. A practical document is necessary that establishes the general lines of action against this infection, from Family and Co...

» The mental health of Russian society and social well-being: the social economic aspects
10/05/25 20:00 from sars-cov-2
All over the world, technologies, globalization, demographic shifts, emergency situations and climate changes are altering conditions how and where people live and work. In many countries, the COVID-19 pandemic and geopolitical crises im...

» Advances in COVID-19 Therapeutics: Exploring the Role of Lectins and Protease Inhibitors
10/05/25 20:00 from coronavirus
The rapid global spread of SARS-CoV-2 has demanded innovative approaches to treatment and prevention. This article reviews the current landscape of COVID-19 therapeutics and vaccines, emphasizing the role of biotechnological products, pa...

» PREgnancy Care Integrating translational Science, Everywhere (PRECISE): a prospective cohort study of African pregnant and non-pregnant women to investigate placental disorders - cohort profile
10/05/25 20:00 from covid-19
PURPOSE: The PREgnancy Care Integrating translational Science, Everywhere Network was established to investigate specific placental disorders (pregnancy hypertension, preterm birth, fetal growth restriction and stillbirth) in sub-Saharan...

» The mortality of adult population from after-troubles of cerebrovascular diseases in the Russian Federation: the territorial differences
10/05/25 20:00 from sars-cov-2
The purpose of the study is to investigate trends in adult population mortality from consequences of cerebrovascular diseases (CVD) as primary cause of death in the Subjects of the Russian Federation and the Federal Okrugs (FO) before an...

» Investigation of trial registration as part of a research integrity assessment of randomised controlled trials in COVID-19 evidence syntheses: a meta-epidemiological study
10/05/25 20:00 from covid-19
CONCLUSIONS: If prospective trial registration is required for inclusion in evidence syntheses, only 6 out of 10 COVID-19 RCTs would be eligible. Restricting eligibility to prospectively registered RCTs would include most large and inter...

» SARS-CoV-2 Infection Reactivates HIV-1 Replication From Latency in U1 Cells
10/05/25 20:00 from sars-cov-2
The global impact of COVID-19, caused by SARS-CoV-2, has infected millions, including those with HIV-1. However, it is unclear if SARS-CoV-2 affects HIV-1 reactivation from latency. Here, we used the U1 cell line to explore how SARS-CoV-...

» Uncertainty and decision-making in critical care: lessons from managing COVID-19 ARDS in preparation for the next pandemic
10/05/25 20:00 from covid-19
CONCLUSION: Future pandemic preparedness programmes should target modifiable influences such as information sharing, teamworking and resource limitations to mitigate against the negative influence of uncertainty and thereby improve decis...

» Palmitoylated COX-2^Cys555 reprogramed mitochondrial metabolism in pyroptotic inflammatory injury in patients with post-acute COVID-19 syndrome
10/05/25 20:00 from sars-cov-2 spike protein
CONCLUSION: This study highlights the regulatory role of COX-2^(Cys555) palmitoylation in mitochondrial metabolism and lung inflammatory injury, and suggests potential therapeutic targets to combat respiratory pathogenesis linked to palm...

» The Republic of Korea's post-COVID-19 pandemic preparedness: it is time to assess the progress of pandemic preparedness
10/05/25 20:00 from covid-19
No abstract

» Introduction to burnout and well-being for anesthesiologists in South Korea: narrative and brief review
10/05/25 20:00 from covid-19
Burnout is a widespread occupational issue in the medical field, posing significant risks to both physician health and patient care worldwide. While the COVID-19 pandemic highlighted the impact of systemic factors-such as excessive workl...

» Advances in COVID-19 Therapeutics: Exploring the Role of Lectins and Protease Inhibitors
10/05/25 20:00 from covid-19
The rapid global spread of SARS-CoV-2 has demanded innovative approaches to treatment and prevention. This article reviews the current landscape of COVID-19 therapeutics and vaccines, emphasizing the role of biotechnological products, pa...

» Network modeling of the different SARS-CoV-2 spike protein infection points within the human hematopoietic network
10/05/25 20:00 from sars-cov-2 spike protein
Hematopoiesis is a physiological process that mainly functions in both the formation and replenishment of varying types of blood cells. SARS-CoV-2 has been reported to affect the human hematopoietic system at multiple infection points le...

» The LDL receptor related protein 1 (LRP1) facilitates ACE2-mediated endocytosis of SARS-CoV2 spike protein-containing pseudovirions
10/05/25 20:00 from sars-cov-2 spike protein
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, employs the viral spike (S) protein to associate with host cells. While angiotensin-converting enzyme 2 (ACE2) is a major receptor for the SAR...

» Hybrid and Vaccination Immunity Against Severe COVID-19 in the Post-Pandemic Era - a Retrospective Cohort Study
10/05/25 20:00 from covid-19
CONCLUSIONS: At this post-pandemic stage, individuals with hybrid immunity had a significantly lower risk of severe disease. These findings support the prioritization of protection strategies for individuals without hybrid immunity and s...

» Palmitoylated COX-2(Cys555) reprogramed mitochondrial metabolism in pyroptotic inflammatory injury in patients with post-acute COVID-19 syndrome
10/05/25 20:00 from covid-19
CONCLUSION: This study highlights the regulatory role of COX-2^(Cys555) palmitoylation in mitochondrial metabolism and lung inflammatory injury, and suggests potential therapeutic targets to combat respiratory pathogenesis linked to palm...

» Palmitoylated COX-2^Cys555 reprogramed mitochondrial metabolism in pyroptotic inflammatory injury in patients with post-acute COVID-19 syndrome
10/05/25 20:00 from coronavirus
CONCLUSION: This study highlights the regulatory role of COX-2^(Cys555) palmitoylation in mitochondrial metabolism and lung inflammatory injury, and suggests potential therapeutic targets to combat respiratory pathogenesis linked to palm...

» Modeling the effects of cross immunity and control measures on competitive dynamics of SARS-CoV-2 variants in the USA, UK, and Brazil
10/05/25 20:00 from covid-19
Mutation in the SARS-CoV-2 virus may lead to the evolution of new variants. The dynamics of these variants varied among countries. Identification of the governing factors responsible for distinctions in their dynamics is important for pr...

» The LDL receptor related protein 1 (LRP1) facilitates ACE2-mediated endocytosis of SARS-CoV2 spike protein-containing pseudovirions
10/05/25 20:00 from coronavirus
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, employs the viral spike (S) protein to associate with host cells. While angiotensin-converting enzyme 2 (ACE2) is a major receptor for the SAR...

» Network modeling of the different SARS-CoV-2 spike protein infection points within the human hematopoietic network
10/05/25 20:00 from covid-19
Hematopoiesis is a physiological process that mainly functions in both the formation and replenishment of varying types of blood cells. SARS-CoV-2 has been reported to affect the human hematopoietic system at multiple infection points le...

» Impact of long COVID on the health-related quality of life of Japanese patients: A prospective nationwide cohort study
10/05/25 20:00 from coronavirus
CONCLUSIONS: Long COVID symptoms were associated with lower physical and mental HRQoL. Severe outcomes of COVID-19 impacted PCS but not MCS.

» The mental health of Russian society and social well-being: the social economic aspects
10/05/25 20:00 from coronavirus
All over the world, technologies, globalization, demographic shifts, emergency situations and climate changes are altering conditions how and where people live and work. In many countries, the COVID-19 pandemic and geopolitical crises im...

» PREgnancy Care Integrating translational Science, Everywhere (PRECISE): a prospective cohort study of African pregnant and non-pregnant women to investigate placental disorders - cohort profile
10/05/25 20:00 from Covid-19 origins
PURPOSE: The PREgnancy Care Integrating translational Science, Everywhere Network was established to investigate specific placental disorders (pregnancy hypertension, preterm birth, fetal growth restriction and stillbirth) in sub-Saharan...

» The mortality of adult population from after-troubles of cerebrovascular diseases in the Russian Federation: the territorial differences
10/05/25 20:00 from coronavirus
The purpose of the study is to investigate trends in adult population mortality from consequences of cerebrovascular diseases (CVD) as primary cause of death in the Subjects of the Russian Federation and the Federal Okrugs (FO) before an...

» Past But Not Forgotten: Innate Factors Affect the Course of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Patients With Inflammatory Bowel Disease
10/05/25 20:00 from coronavirus
No abstract

» SARS-CoV-2 Infection Reactivates HIV-1 Replication From Latency in U1 Cells
10/05/25 20:00 from coronavirus
The global impact of COVID-19, caused by SARS-CoV-2, has infected millions, including those with HIV-1. However, it is unclear if SARS-CoV-2 affects HIV-1 reactivation from latency. Here, we used the U1 cell line to explore how SARS-CoV-...

» Correction to: Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release
09/05/25 20:00 from sars-cov-2
No abstract

» Association Between Pre-Diagnostic Delay and Survival Among Patients With Esophageal and Gastric Cancer Treated With Curative Intent During the COVID19 Pandemic
09/05/25 20:00 from sars-cov-2
CONCLUSION: The COVID19 pandemic caused significant diagnostic delay for patients presenting with curative gastroesophageal and gastric cancer. The lack of correlation of pre-diagnostic interval with OS may reflect underlying tumor biolo...

» Rohino-Orbital-Cerebral Mycosis (ROCM) Attributable to Candida krusei Infection After COVID-19
09/05/25 20:00 from covid-19
No abstract

» Elevated Plasma Levels of NET Components in Men with Severe COVID-19 Correlates to Increased Amounts of IL-18
09/05/25 20:00 from sars-cov-2
Severe COVID-19 disease is accompanied by high plasma levels of proinflammatory, prothrombotic NETs, and NET-inducing cytokine IL-18. We found that both, IL-18 and NETs, are elevated in men with severe disease, but not in women of the sa...

» COVID-19 Knowledge, Message Perceptions and Behaviors among Pregnant and Postpartum Women During the Early Months of the COVID-19 Pandemic in the United States
09/05/25 20:00 from covid-19
OBJECTIVES: This study examined the factors associated with COVID-19 knowledge, perceptions of COVID-19 messaging related to the perinatal population, and examined the association between COVID-19 knowledge and adherence to COVID-19 prev...

» Advancing ORFV-Based Therapeutics to the Clinical Stage
09/05/25 20:00 from sars-cov-2
The Orf virus (ORFV) is the prototype member of the parapoxvirus family and has long been recognized for its robust immunogenicity, favourable safety profile and its ability to stimulate both cellular and humoural immune responses withou...

» Location planning, resource reallocation and patient assignment during a pandemic considering the needs of ordinary patients
09/05/25 20:00 from covid-19
During the initial phase of a pandemic outbreak, the rapid increase in the number of infected patients leads to shortages of medical resources for both pandemic-related and non-pandemic (ordinary) patients. It is crucial to efficiently u...

» Association Between Pre-Diagnostic Delay and Survival Among Patients With Esophageal and Gastric Cancer Treated With Curative Intent During the COVID19 Pandemic
09/05/25 20:00 from coronavirus
CONCLUSION: The COVID19 pandemic caused significant diagnostic delay for patients presenting with curative gastroesophageal and gastric cancer. The lack of correlation of pre-diagnostic interval with OS may reflect underlying tumor biolo...

» Correction to: Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release
09/05/25 20:00 from covid-19
No abstract

» In vitro assessment of portable, domestic UV-C disinfection devices' effects on skin fibroblasts
09/05/25 20:00 from covid-19
CONCLUSION: The results provide evidence regarding the cutaneous photodamaging effects of commercially available UV-C disinfection devices for domestic use at the cellular level, contributing to the UV-C disinfection devices' risk manage...

» Elevated Plasma Levels of NET Components in Men with Severe COVID-19 Correlates to Increased Amounts of IL-18
09/05/25 20:00 from coronavirus
Severe COVID-19 disease is accompanied by high plasma levels of proinflammatory, prothrombotic NETs, and NET-inducing cytokine IL-18. We found that both, IL-18 and NETs, are elevated in men with severe disease, but not in women of the sa...

» Replacing PEG-Lipid with Amphiphilic Polycarbonates in mRNA-Loaded Lipid Nanoparticles: Impact of Polycarbonate Structure on Physicochemical and Transfection Properties
09/05/25 20:00 from covid-19
Since the remarkable breakthrough of COVID-19 mRNA vaccines, lipid nanoparticles (LNPs) have gained substantial attention as the most cutting-edge clinical formulations for mRNA delivery. PEGylated lipid (PEG-lipid) has been regarded as ...

» Advancing ORFV-Based Therapeutics to the Clinical Stage
09/05/25 20:00 from coronavirus
The Orf virus (ORFV) is the prototype member of the parapoxvirus family and has long been recognized for its robust immunogenicity, favourable safety profile and its ability to stimulate both cellular and humoural immune responses withou...

» Newborn screening programs promote vaccine acceptance among parents in Turkey: a cross-sectional study
09/05/25 20:00 from covid-19
CONCLUSION: This study found lower vaccine hesitancy among participants in newborn screening programs and those whose parents received adult vaccinations, potentially due to increased contact with health professionals and greater health-...

» The interaction of COVID-19 and sociodemographic factors on pediatric rehabilitation service initiation
09/05/25 20:00 from covid-19
CONCLUSIONS: Policies and procedures are needed to address disparities that existed prior to and during COVID in rehabilitation services access. It is critical to screen children for rehabilitation needs that may have gone untreated duri...

» Association Between Pre-Diagnostic Delay and Survival Among Patients With Esophageal and Gastric Cancer Treated With Curative Intent During the COVID19 Pandemic
09/05/25 20:00 from covid-19
CONCLUSION: The COVID19 pandemic caused significant diagnostic delay for patients presenting with curative gastroesophageal and gastric cancer. The lack of correlation of pre-diagnostic interval with OS may reflect underlying tumor biolo...

» The "Whole-Of-Society" Approach for Misinformation Correction: How Expert Didactic TikTok Videos Motivate Citizen Fact-Checking and Vaccine Promotion
09/05/25 20:00 from covid-19
This study employs an experimental design to examine the effects of expert didactic corrective TikTok videos on motivating people's intentions to engage in citizen fact-checking and vaccine promotion. Our findings reveal that participant...

» The where and the why: sources of information about COVID-19 vaccines among migrants in Australia
09/05/25 20:00 from covid-19
CONCLUSION: To ensure equitable access to health information, health communications should be tailored to migrants' specific needs, preferences and information-gathering capacity. Such communication should be practised in all aspects of ...

» Walter Patrick Memorial Lecture: Building Resilience in Families and Communities in Times of Crisis
09/05/25 20:00 from covid-19
This article looks into the memorial lecture delivered by Professor Dr Wah Yun Low in memory of the late Professor Walter K. Patrick, focusing on building resilience within families and communities in the aftermath of COVID-19. This arti...

» Elevated Plasma Levels of NET Components in Men with Severe COVID-19 Correlates to Increased Amounts of IL-18
09/05/25 20:00 from covid-19
Severe COVID-19 disease is accompanied by high plasma levels of proinflammatory, prothrombotic NETs, and NET-inducing cytokine IL-18. We found that both, IL-18 and NETs, are elevated in men with severe disease, but not in women of the sa...

» Advancing ORFV-Based Therapeutics to the Clinical Stage
09/05/25 20:00 from covid-19
The Orf virus (ORFV) is the prototype member of the parapoxvirus family and has long been recognized for its robust immunogenicity, favourable safety profile and its ability to stimulate both cellular and humoural immune responses withou...

» Association Between Pre-Diagnostic Delay and Survival Among Patients With Esophageal and Gastric Cancer Treated With Curative Intent During the COVID19 Pandemic
09/05/25 20:00 from coronavirus
CONCLUSION: The COVID19 pandemic caused significant diagnostic delay for patients presenting with curative gastroesophageal and gastric cancer. The lack of correlation of pre-diagnostic interval with OS may reflect underlying tumor biolo...

» Elevated Plasma Levels of NET Components in Men with Severe COVID-19 Correlates to Increased Amounts of IL-18
09/05/25 20:00 from coronavirus
Severe COVID-19 disease is accompanied by high plasma levels of proinflammatory, prothrombotic NETs, and NET-inducing cytokine IL-18. We found that both, IL-18 and NETs, are elevated in men with severe disease, but not in women of the sa...

» Advancing ORFV-Based Therapeutics to the Clinical Stage
09/05/25 20:00 from coronavirus
The Orf virus (ORFV) is the prototype member of the parapoxvirus family and has long been recognized for its robust immunogenicity, favourable safety profile and its ability to stimulate both cellular and humoural immune responses withou...

» Correction to: Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release
09/05/25 20:00 from sars-cov-2
No abstract

» Rohino-Orbital-Cerebral Mycosis (ROCM) Attributable to Candida krusei Infection After COVID-19
09/05/25 20:00 from covid-19
No abstract

» COVID-19 Knowledge, Message Perceptions and Behaviors among Pregnant and Postpartum Women During the Early Months of the COVID-19 Pandemic in the United States
09/05/25 20:00 from covid-19
OBJECTIVES: This study examined the factors associated with COVID-19 knowledge, perceptions of COVID-19 messaging related to the perinatal population, and examined the association between COVID-19 knowledge and adherence to COVID-19 prev...

» Association Between Pre-Diagnostic Delay and Survival Among Patients With Esophageal and Gastric Cancer Treated With Curative Intent During the COVID19 Pandemic
09/05/25 20:00 from sars-cov-2
CONCLUSION: The COVID19 pandemic caused significant diagnostic delay for patients presenting with curative gastroesophageal and gastric cancer. The lack of correlation of pre-diagnostic interval with OS may reflect underlying tumor biolo...

» Location planning, resource reallocation and patient assignment during a pandemic considering the needs of ordinary patients
09/05/25 20:00 from covid-19
During the initial phase of a pandemic outbreak, the rapid increase in the number of infected patients leads to shortages of medical resources for both pandemic-related and non-pandemic (ordinary) patients. It is crucial to efficiently u...

» Elevated Plasma Levels of NET Components in Men with Severe COVID-19 Correlates to Increased Amounts of IL-18
09/05/25 20:00 from sars-cov-2
Severe COVID-19 disease is accompanied by high plasma levels of proinflammatory, prothrombotic NETs, and NET-inducing cytokine IL-18. We found that both, IL-18 and NETs, are elevated in men with severe disease, but not in women of the sa...

» Correction to: Elevated serum mtDNA in COVID-19 patients is linked to SARS-CoV-2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release
09/05/25 20:00 from covid-19
No abstract

» Advancing ORFV-Based Therapeutics to the Clinical Stage
09/05/25 20:00 from sars-cov-2
The Orf virus (ORFV) is the prototype member of the parapoxvirus family and has long been recognized for its robust immunogenicity, favourable safety profile and its ability to stimulate both cellular and humoural immune responses withou...

» In vitro assessment of portable, domestic UV-C disinfection devices' effects on skin fibroblasts
09/05/25 20:00 from covid-19
CONCLUSION: The results provide evidence regarding the cutaneous photodamaging effects of commercially available UV-C disinfection devices for domestic use at the cellular level, contributing to the UV-C disinfection devices' risk manage...

» Replacing PEG-Lipid with Amphiphilic Polycarbonates in mRNA-Loaded Lipid Nanoparticles: Impact of Polycarbonate Structure on Physicochemical and Transfection Properties
09/05/25 20:00 from covid-19
Since the remarkable breakthrough of COVID-19 mRNA vaccines, lipid nanoparticles (LNPs) have gained substantial attention as the most cutting-edge clinical formulations for mRNA delivery. PEGylated lipid (PEG-lipid) has been regarded as ...

» Newborn screening programs promote vaccine acceptance among parents in Turkey: a cross-sectional study
09/05/25 20:00 from covid-19
CONCLUSION: This study found lower vaccine hesitancy among participants in newborn screening programs and those whose parents received adult vaccinations, potentially due to increased contact with health professionals and greater health-...

» The interaction of COVID-19 and sociodemographic factors on pediatric rehabilitation service initiation
09/05/25 20:00 from covid-19
CONCLUSIONS: Policies and procedures are needed to address disparities that existed prior to and during COVID in rehabilitation services access. It is critical to screen children for rehabilitation needs that may have gone untreated duri...

» Association Between Pre-Diagnostic Delay and Survival Among Patients With Esophageal and Gastric Cancer Treated With Curative Intent During the COVID19 Pandemic
09/05/25 20:00 from covid-19
CONCLUSION: The COVID19 pandemic caused significant diagnostic delay for patients presenting with curative gastroesophageal and gastric cancer. The lack of correlation of pre-diagnostic interval with OS may reflect underlying tumor biolo...

» The "Whole-Of-Society" Approach for Misinformation Correction: How Expert Didactic TikTok Videos Motivate Citizen Fact-Checking and Vaccine Promotion
09/05/25 20:00 from covid-19
This study employs an experimental design to examine the effects of expert didactic corrective TikTok videos on motivating people's intentions to engage in citizen fact-checking and vaccine promotion. Our findings reveal that participant...

» The where and the why: sources of information about COVID-19 vaccines among migrants in Australia
09/05/25 20:00 from covid-19
CONCLUSION: To ensure equitable access to health information, health communications should be tailored to migrants' specific needs, preferences and information-gathering capacity. Such communication should be practised in all aspects of ...

» Walter Patrick Memorial Lecture: Building Resilience in Families and Communities in Times of Crisis
09/05/25 20:00 from covid-19
This article looks into the memorial lecture delivered by Professor Dr Wah Yun Low in memory of the late Professor Walter K. Patrick, focusing on building resilience within families and communities in the aftermath of COVID-19. This arti...

» Elevated Plasma Levels of NET Components in Men with Severe COVID-19 Correlates to Increased Amounts of IL-18
09/05/25 20:00 from covid-19
Severe COVID-19 disease is accompanied by high plasma levels of proinflammatory, prothrombotic NETs, and NET-inducing cytokine IL-18. We found that both, IL-18 and NETs, are elevated in men with severe disease, but not in women of the sa...

» Advancing ORFV-Based Therapeutics to the Clinical Stage
09/05/25 20:00 from covid-19
The Orf virus (ORFV) is the prototype member of the parapoxvirus family and has long been recognized for its robust immunogenicity, favourable safety profile and its ability to stimulate both cellular and humoural immune responses withou...

» Structural basis of TMPRSS11D specificity and autocleavage activation
09/05/25 20:00 from Cell entry mechanisms of SARS-CoV-2
Transmembrane Protease, Serine-2 (TMPRSS2) and TMPRSS11D are human proteases that enable SARS-CoV-2 and Influenza A/B virus infections, but their biochemical mechanisms for facilitating viral cell entry remain unclear. We show these prot...

» Designing a multi-epitope universal vaccine for concurrent infections of SARS-CoV-2 and influenza viruses using an immunoinformatics approach
09/05/25 20:00 from coronavirus
CONCLUSION: Overall, the findings suggest that the designed vaccine has the potential to serve as an effective universal vaccine and a promising strategy for controlling both Coronavirus disease 2019 (COVID-19) and influenza on a global ...

» A new framework for disentangling different components of excess mortality applied to Dutch care home residents during Covid-19
09/05/25 20:00 from coronavirus
CONCLUSIONS: Our approach offers a new perspective on how to model and interpret excess mortality in vulnerable groups during a crisis and provides a methodological foundation for investigating excess excess mortality in other contexts.

» Developing an intuitive decision support system for equitable vaccine distribution during pandemics
09/05/25 20:00 from coronavirus
Effective organization of the vaccine supply chain is vital to achieve high vaccination rates in pandemics. This paper presents a novel approach for developing a decision support system (DSS) to support health officials and policymakers ...

» Structural basis of TMPRSS11D specificity and autocleavage activation
09/05/25 20:00 from coronavirus
Transmembrane Protease, Serine-2 (TMPRSS2) and TMPRSS11D are human proteases that enable SARS-CoV-2 and Influenza A/B virus infections, but their biochemical mechanisms for facilitating viral cell entry remain unclear. We show these prot...

» Designing, Implementing, and Adapting Virtual Care Models for Marginalized Communities
09/05/25 20:00 from coronavirus
Telehealth and virtual care models are viable solutions to disparities impacting diverse or marginalized communities with endocrine disorders. Racially and ethnically diverse children with endocrine disorders and their families have not ...

» Verbenalin protects against coronavirus pneumonia by promoting host immune homeostasis: Evidences for its mechanism of action
09/05/25 20:00 from coronavirus
CONCLUSION: Verbenalin enhances PINK1/Parkin-mediated mitophagy to suppress NLRP3 activation, thereby promoting immune homeostasis and mitigating HCoV-229E-induced inflammation.

» Evaluation of biofilm formation, antimicrobial pattern, and typing of Stenotrophomonas maltophilia isolated from clinical sources in Brazil
08/05/25 20:00 from Covid-19 origins
This study aimed to evaluate the biofilm formation and disinfectant tolerance of Stenotrophomonas maltophilia strains originated from hospitalized patients during the COVID-19 pandemic. Nine strains were isolated from different clinical ...

» Secondary exposure and risk assessment of biocides as disinfectant sprays for COVID-19 prevention
08/05/25 20:00 from coronavirus
The importance of disinfection has recently increased owing to the spread of infections, such as coronavirus disease 2019 (COVID-19). However, exposure to the biocidal products used for disinfection poses health risks. This study aimed t...

» Secondary exposure and risk assessment of biocides as disinfectant sprays for COVID-19 prevention
08/05/25 20:00 from covid-19
The importance of disinfection has recently increased owing to the spread of infections, such as coronavirus disease 2019 (COVID-19). However, exposure to the biocidal products used for disinfection poses health risks. This study aimed t...

» New Onset of Primary Membranous Nephropathy After COVID-19 mRNA Vaccination in Affected Sjögren's Syndrome
08/05/25 20:00 from coronavirus
The global administration of mRNA vaccines in response to the coronavirus disease 2019 (COVID-19) pandemic has been crucial in mitigating the spread of the virus. While these vaccines are generally safe and effective, there have been occ...

» Impact of the COVID-19 pandemic on lifestyle habits and body weight of military flying personnel of the Polish Armed Forces
08/05/25 20:00 from coronavirus
CONCLUSIONS: The COVID-19 pandemic condition did not disrupt the existing lifestyles of most military flying personnel. More than half of the military flying personnel surveyed reported no effect of the COVID-19 pandemic on weight change...

» New Onset of Primary Membranous Nephropathy After COVID-19 mRNA Vaccination in Affected Sjogren's Syndrome
08/05/25 20:00 from covid-19
The global administration of mRNA vaccines in response to the coronavirus disease 2019 (COVID-19) pandemic has been crucial in mitigating the spread of the virus. While these vaccines are generally safe and effective, there have been occ...

» An adjuvanted chimeric spike antigen boosts lung-resident memory T-cells and induces pan-sarbecovirus protective immunity
08/05/25 20:00 from coronavirus
Next-generation vaccines are essential to address the evolving nature of SARS-CoV-2 and to protect against emerging pandemic threats from other coronaviruses. These vaccines should elicit broad protection, provide long-lasting immunity a...

» Survival and prognostic factors in rhino-orbito-cerebral mucormycosis: A 3-year cohort study
08/05/25 20:00 from covid-19
Mucormycosis, a severe fungal infection, has exhibited a concerning increase in recent years, particularly during the COVID-19 outbreak. This three-year cohort study aims to investigate an overview of the epidemiology, clinical and radio...

» Rapid antigen test based on gold nanoparticles embedded with highly sensitive surface-enhanced Raman scattering probes for detecting antigen concentrations below the visual detection limit
08/05/25 20:00 from coronavirus
The COVID-19 pandemic has proven that people expect medically high accuracy, sensitivity, and rapid testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection. These needs have led to developing various testing me...

» Post-Discharge COVID-19 Symptoms Predict 1-Year Functional Decline, Falls, and Emergency Department Visits: A Cohort Study
08/05/25 20:00 from covid-19
CONCLUSIONS: Persistent symptoms after hospitalization are common and contribute to functional decline, falls, and ED visits in older COVID-19 survivors. These findings suggest that greater attention to symptom burden may support risk id...

» The characteristics of multimodal fundus imaging in AMN patients following COVID infection
08/05/25 20:00 from coronavirus
We investigated the features of multimodal fundus imaging in patients with both Coronavirus disease 2019 (COVID-19) and acute macular neuroretinopathy (AMN). This study included 15 patients with 29 eyes, all of whom underwent comprehensi...

» Impact of the COVID-19 pandemic on lifestyle habits and body weight of military flying personnel of the Polish Armed Forces
08/05/25 20:00 from covid-19
CONCLUSIONS: The COVID-19 pandemic condition did not disrupt the existing lifestyles of most military flying personnel. More than half of the military flying personnel surveyed reported no effect of the COVID-19 pandemic on weight change...

» Relationship between psychosocial problems and satisfaction with GP communication in German primary care practices: a structural equation model based on the cross-sectional GPCare-1 patient study
08/05/25 20:00 from coronavirus
CONCLUSIONS: GPs should be aware of the high occurrence of patients' psychosocial problems and actively address patients' social support and self-management preferences which influence patients' satisfaction with GP communication.

» An adjuvanted chimeric spike antigen boosts lung-resident memory T-cells and induces pan-sarbecovirus protective immunity
08/05/25 20:00 from sars-cov-2
Next-generation vaccines are essential to address the evolving nature of SARS-CoV-2 and to protect against emerging pandemic threats from other coronaviruses. These vaccines should elicit broad protection, provide long-lasting immunity a...

» Understanding intentions to use a multi-component supported self-management platform for long COVID-19: a mixed-methods evaluation in Hong Kong
08/05/25 20:00 from covid-19
A culturally appropriate, multi-component self-management platform was developed to facilitate Long COVID-19 recovery in Hong Kong, comprising a smartphone application, a website, and a customer relationship management (CRM)-based messag...

» Diagnostic biomarkers and immune infiltration profiles common to COVID-19, acute myocardial infarction and acute ischaemic stroke using bioinformatics methods and machine learning
08/05/25 20:00 from Cell entry mechanisms of SARS-CoV-2
CONCLUSION: We employed bioinformatics methods and machine learning to investigate common diagnostic biomarkers and immune infiltration characteristics of COVID-19, AMI and AIS. Functional and pathway analyses indicated that the co-DEGs ...

» The published role of artificial intelligence in drug discovery and development: a bibliometric and social network analysis from 1990 to 2023
08/05/25 20:00 from coronavirus
Today, drug discovery and development is one of the fields where Artificial Intelligence (AI) is used extensively. Therefore, this study aims to systematically analyze the scientific literature on the application of AI in drug discovery ...

» Probabilistic analysis of ground settlement induced by soil and rock composite foundation excavation considering spatial variability
08/05/25 20:00 from covid-19
The deposition processes of geotechnical materials are inherently complex, resulting in significant spatial variability in soil and rock properties. This study proposes a probabilistic framework applicable to braced excavations in compos...

» Physical activity levels and psychological parameters among university students following the COVID-19 pandemic
08/05/25 20:00 from coronavirus
CONCLUSIONS: Results indicated that higher levels of PA among university students were positively associated with increased self-confidence, self-efficacy, and psychological resilience. Consequently, by facilitating the organization of d...

» Exhaled breath protein composition in patients hospitalized during the first wave of COVID-19
08/05/25 20:00 from sars-cov-2
COVID-19 leads to substantial morbidity and excess mortality all over the world which may be aggravated by the propensity of SARS-CoV-2 to mutate. Mechanisms for development of severe COVID-19 are poorly understood. The air we exhale con...

» Engineered bacteria as an orally administered anti-viral treatment and immunization system
08/05/25 20:00 from sars-cov-2 spike protein
The emergence of new viral pathogens necessitates innovative antiviral therapies and vaccines. Traditional approaches, such as monoclonal antibodies and vaccines, are often hindered by resistance, limited effectiveness, and high costs. H...

» An adjuvanted chimeric spike antigen boosts lung-resident memory T-cells and induces pan-sarbecovirus protective immunity
08/05/25 20:00 from covid-19
Next-generation vaccines are essential to address the evolving nature of SARS-CoV-2 and to protect against emerging pandemic threats from other coronaviruses. These vaccines should elicit broad protection, provide long-lasting immunity a...

» Rapid antigen test based on gold nanoparticles embedded with highly sensitive surface-enhanced Raman scattering probes for detecting antigen concentrations below the visual detection limit
08/05/25 20:00 from sars-cov-2
The COVID-19 pandemic has proven that people expect medically high accuracy, sensitivity, and rapid testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection. These needs have led to developing various testing me...

» Multiple Lines of Treatment in a Patient with Small Cell Neuroendocrine Carcinoma of the Cervix: A Case Report
08/05/25 20:00 from coronavirus
Small cell neuroendocrine carcinoma of the cervix (SCNEC) is a rare and highly aggressive tumor with a high rate of recurrence and metastasis. Due to its low prevalence, standardized treatment regimens for SCNEC remain undefined. This ca...

» Vonoprazan-based therapy versus standard regimen for Helicobacter pylori infection management in Egypt: an open-label randomized controlled trial
08/05/25 20:00 from covid-19
As antibiotic resistance continues to rise, the development of novel H. pylori treatment regimens, combined with regular assessment of existing treatment regimens, is imperative. The study evaluates the efficacy, safety, and compliance o...

» A conceptual and computational framework for modeling the complex, adaptive dynamics of epidemics: The case of the SARS-CoV-2 pandemic in Mexico
08/05/25 20:00 from sars-cov-2
In the quest to ensure adequate preparedness for health emergencies caused by infectious disease pandemics, there is a need for tools that can address the myriad relevant questions related to the spread and trajectory of pandemics. A hyb...

» Engineered bacteria as an orally administered anti-viral treatment and immunization system
08/05/25 20:00 from coronavirus
The emergence of new viral pathogens necessitates innovative antiviral therapies and vaccines. Traditional approaches, such as monoclonal antibodies and vaccines, are often hindered by resistance, limited effectiveness, and high costs. H...

» Genome-wide association study of myocarditis and pericarditis following COVID-19 vaccination
08/05/25 20:00 from covid-19
This genome-wide association study (GWAS) explores the genetic components of severe adverse events following COVID-19 vaccination, with focus on myocarditis and pericarditis. Three SNPs (rs536572545, rs146289966 and rs142297026) near the...

» Influence of anti-Spike protein antibody levels on tocilizumab efficacy in hospitalized patients with severe COVID-19 pneumonia: a post-hoc analysis of the COVACTA trial
08/05/25 20:00 from sars-cov-2 spike protein
CONCLUSIONS: Our findings suggest that using IL-6 inhibitors in severe COVID-19 patients with low S-spike antibody titers may improve clinical outcomes.

» Identifying most important predictors for suicidal thoughts and behaviours among healthcare workers active during the Spain COVID-19 pandemic: a machine-learning approach
08/05/25 20:00 from coronavirus
CONCLUSIONS: Machine learning-based prediction models for STBs in HCWs during the COVID-19 pandemic trained on web-based survey data present high discrimination and classification capacity. Future clinical implementations of this model c...

» Cancer type and gene signatures associated with breakthrough infections following COVID-19 mRNA vaccination
08/05/25 20:00 from covid-19
We used epidemiological data from 21195 patients with cancer and 180407 matched controls, including in-depth analyses in 216 cancer patients, to discover clinical and molecular determinants that predispose cancer patients to breakthrough...

» Relationship between psychosocial problems and satisfaction with GP communication in German primary care practices: a structural equation model based on the cross-sectional GPCare-1 patient study
08/05/25 20:00 from sars-cov-2
CONCLUSIONS: GPs should be aware of the high occurrence of patients' psychosocial problems and actively address patients' social support and self-management preferences which influence patients' satisfaction with GP communication.

» Reproducibility of genetic risk factors identified for long COVID using combinatorial analysis across US and UK patient cohorts with diverse ancestries
08/05/25 20:00 from coronavirus
CONCLUSION: These results demonstrate the reproducibility of long COVID disease signal found by combinatorial analysis, broadly validating the results of the original analysis. They provide compelling evidence for a much broader array of...

» Exhaled breath protein composition in patients hospitalized during the first wave of COVID-19
08/05/25 20:00 from covid-19
COVID-19 leads to substantial morbidity and excess mortality all over the world which may be aggravated by the propensity of SARS-CoV-2 to mutate. Mechanisms for development of severe COVID-19 are poorly understood. The air we exhale con...

» Influence of anti-Spike protein antibody levels on tocilizumab efficacy in hospitalized patients with severe COVID-19 pneumonia: a post-hoc analysis of the COVACTA trial
08/05/25 20:00 from coronavirus
CONCLUSIONS: Our findings suggest that using IL-6 inhibitors in severe COVID-19 patients with low S-spike antibody titers may improve clinical outcomes.

» Multiple Lines of Treatment in a Patient with Small Cell Neuroendocrine Carcinoma of the Cervix: A Case Report
08/05/25 20:00 from sars-cov-2
Small cell neuroendocrine carcinoma of the cervix (SCNEC) is a rare and highly aggressive tumor with a high rate of recurrence and metastasis. Due to its low prevalence, standardized treatment regimens for SCNEC remain undefined. This ca...

» Evaluation of biofilm formation, antimicrobial pattern, and typing of Stenotrophomonas maltophilia isolated from clinical sources in Brazil
08/05/25 20:00 from covid-19
This study aimed to evaluate the biofilm formation and disinfectant tolerance of Stenotrophomonas maltophilia strains originated from hospitalized patients during the COVID-19 pandemic. Nine strains were isolated from different clinical ...

» The clinical impact of prolonged steroid therapy in severe COVID-19 patients: a retrospective cohort study with propensity score matching
08/05/25 20:00 from coronavirus
CONCLUSIONS: Prolonged steroid therapy beyond 10 days did not improve survival or other clinical outcomes in patients with severe COVID-19, suggesting that early steroid withdrawal may be appropriate for selected patients.

» Engineered bacteria as an orally administered anti-viral treatment and immunization system
08/05/25 20:00 from sars-cov-2
The emergence of new viral pathogens necessitates innovative antiviral therapies and vaccines. Traditional approaches, such as monoclonal antibodies and vaccines, are often hindered by resistance, limited effectiveness, and high costs. H...

» Rapid antigen test based on gold nanoparticles embedded with highly sensitive surface-enhanced Raman scattering probes for detecting antigen concentrations below the visual detection limit
08/05/25 20:00 from covid-19
The COVID-19 pandemic has proven that people expect medically high accuracy, sensitivity, and rapid testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection. These needs have led to developing various testing me...

» Identifying most important predictors for suicidal thoughts and behaviours among healthcare workers active during the Spain COVID-19 pandemic: a machine-learning approach
08/05/25 20:00 from sars-cov-2
CONCLUSIONS: Machine learning-based prediction models for STBs in HCWs during the COVID-19 pandemic trained on web-based survey data present high discrimination and classification capacity. Future clinical implementations of this model c...

» Disease burden of rotavirus related diarrhea in children under 5 years in China: a meta-analysis
08/05/25 20:00 from covid-19
Rotavirus (RV) is a leading cause of severe diarrhea among children under five years of age in China. In this meta-analysis, we assessed the disease burden of RV-related diarrhea by analyzing 73 studies retrieved from the PubMed, Web of ...

» Understanding the association of cell-surface proteins (ACE2 and GRP78) facilitating pathogen recognition: a computational approach
08/05/25 20:00 from sars-cov-2
Angiotensin-converting enzyme 2 (ACE2) has been reported to be the primary host cell receptor for recognizing SARS-CoV and SARS-CoV-2 spike proteins. This host-cell element, despite having a crucial role in normal cells, may be hijacked ...

» Reproducibility of genetic risk factors identified for long COVID using combinatorial analysis across US and UK patient cohorts with diverse ancestries
08/05/25 20:00 from sars-cov-2
CONCLUSION: These results demonstrate the reproducibility of long COVID disease signal found by combinatorial analysis, broadly validating the results of the original analysis. They provide compelling evidence for a much broader array of...

» Influence of anti-Spike protein antibody levels on tocilizumab efficacy in hospitalized patients with severe COVID-19 pneumonia: a post-hoc analysis of the COVACTA trial
08/05/25 20:00 from sars-cov-2
CONCLUSIONS: Our findings suggest that using IL-6 inhibitors in severe COVID-19 patients with low S-spike antibody titers may improve clinical outcomes.

» The clinical impact of prolonged steroid therapy in severe COVID-19 patients: a retrospective cohort study with propensity score matching
08/05/25 20:00 from sars-cov-2
CONCLUSIONS: Prolonged steroid therapy beyond 10 days did not improve survival or other clinical outcomes in patients with severe COVID-19, suggesting that early steroid withdrawal may be appropriate for selected patients.

» Peripheral blood cytokine profiles predict the severity of SARS-CoV-2 infection: an EPIC(3) study analysis
08/05/25 20:00 from sars-cov-2
CONCLUSIONS: Cytokine profiles are predictive of SARS-CoV-2 severity in US Veterans and may guide tailored interventions for improved patient management.

» Diagnostic biomarkers and immune infiltration profiles common to COVID-19, acute myocardial infarction and acute ischaemic stroke using bioinformatics methods and machine learning
08/05/25 20:00 from sars-cov-2
CONCLUSION: We employed bioinformatics methods and machine learning to investigate common diagnostic biomarkers and immune infiltration characteristics of COVID-19, AMI and AIS. Functional and pathway analyses indicated that the co-DEGs ...

» Two rounds of the Pandemic Fund at the WHO Eastern Mediterranean Region: progress, lessons learned, challenges, and way forward
08/05/25 20:00 from sars-cov-2
World Health Organization (WHO) played an important role in supporting the Member States of the Eastern Mediterranean Region (EMR) apply for awards from the Pandemic Fund - a vital source of funding for pandemic preparedness and response...

» Cultural practices, healthcare-seeking behaviors, and wildlife interface: Zoonotic disease risks among the Phu Thai Ethnic Group in Thailand
08/05/25 20:00 from Coronavirus origins
CONCLUSION: This study highlights the complex interplay between culture, healthcare access, and zoonotic risks in the Phu Thai community. Enhancing culturally sensitive health education, promoting safe wildlife interaction practices, and...

» Cultural practices, healthcare-seeking behaviors, and wildlife interface: Zoonotic disease risks among the Phu Thai Ethnic Group in Thailand
08/05/25 20:00 from Covid-19 origins
CONCLUSION: This study highlights the complex interplay between culture, healthcare access, and zoonotic risks in the Phu Thai community. Enhancing culturally sensitive health education, promoting safe wildlife interaction practices, and...

» Evaluation of biofilm formation, antimicrobial pattern, and typing of Stenotrophomonas maltophilia isolated from clinical sources in Brazil
08/05/25 20:00 from Covid-19 origins
This study aimed to evaluate the biofilm formation and disinfectant tolerance of Stenotrophomonas maltophilia strains originated from hospitalized patients during the COVID-19 pandemic. Nine strains were isolated from different clinical ...

» COVID-19 infection history as a risk factor for early pregnancy loss: results from the electronic health record-based Southeast Texas COVID and Pregnancy Cohort Study
08/05/25 20:00 from sars-cov-2
CONCLUSIONS: COVID-19 both prior to and during pregnancy was identified as a risk factor for spontaneous abortion in this study sample. These findings highlight the importance of COVID-19 vaccination and post-COVID management for pregnan...

» Prognostic value of functional CT imaging in COVID-ARDS: a two-centre prospective observational study
08/05/25 20:00 from sars-cov-2
CONCLUSIONS: Our data show that in addition to recruitment, the spatial distribution of specific volume change, a surrogate measure of regional lung ventilation, is associated with the risk of death in mechanically ventilated COVID-19 AR...

» Co-production in HIV research: a case study from the COVID-19 pandemic
08/05/25 20:00 from coronavirus
CONCLUSION: Participatory research and co-production are increasingly common approaches to research. These approaches have impacts on all stakeholders involved including co-researchers, public involvement practitioners, academic research...

» Impact of COVID-19 vaccination on symptoms and immune phenotypes in vaccine-naïve individuals with Long COVID
08/05/25 20:00 from sars-cov-2
CONCLUSIONS: In this study of 16 people with Long COVID, vaccination is associated with increased SARS-CoV-2 spike protein-specific IgG and T cell expansion in most participants. Specific immune features are associated with symptom chang...

» Characterizing spatial epidemiology in a heterogeneous transmission landscape using the spatial transmission count statistic
08/05/25 20:00 from sars-cov-2
CONCLUSIONS: In this study, we introduce the Source Sink Score, which determines whether a localized outbreak serves as a source or sink for other regions, and the Local Import Score, which assesses whether the outbreak has transitioned ...

» The Nexus between music classes and psychological wellbeing: the moderating role of sustainable education policy and teachers innovative support in the post Covid-19 era
08/05/25 20:00 from covid-19
PURPOSE: The study was conducted to address the gaps in literature and improve the psychological well-being of Chinese students. For this purpose, the impact of music classes on psychological well-being of the students was investigated. ...

» Epitope mapping of SARS-CoV-2 Spike protein using naturally-acquired immune responses to develop monoclonal antibodies
08/05/25 20:00 from sars-cov-2
COVID-19 vaccination strategies are already available almost worldwide. However, it is also crucial to develop new therapeutic approaches, especially for vulnerable populations that may not fully respond to vaccination, such as the immun...

» Tubulointerstitial nephritis and uveitis post COVID-19 infection in an adult
08/05/25 20:00 from sars-cov-2
A woman in her 50s contracted COVID-19 and initially presented a few weeks afterwards with left eye pain and redness. She was diagnosed with uveitis and treated with glucocorticoid eye drops. Renal impairment was found on laboratory inve...

» Efficacy of initial combination therapy with anti-SARS-CoV-2 antivirals targeting viral clearance in COVID-19 patients with B-cell lymphoma treated with anti-CD20 antibodies: A retrospective single-centre study in Japan
08/05/25 20:00 from sars-cov-2
CONCLUSION: This study showed the potential of early combination antiviral therapy to shorten the time to viral clearance in this high-risk patient population.

» The TyphiNET data visualisation dashboard: unlocking Salmonella Typhi genomics data to support public health
08/05/25 20:00 from coronavirus
CONCLUSIONS: The TyphiNET dashboard provides an interactive platform for accessing genome-derived data on pathogen variant frequencies to inform typhoid control and intervention strategies. The platform is extensible in terms of both dat...

» In-hospital Mortality Among Children and Adults Hospitalized with COVID-19 in Africa Across Pre-Delta, Delta, and Omicron SARS-CoV-2 Waves
08/05/25 20:00 from sars-cov-2
CONCLUSION: Despite a general reduction in mortality risk during Omicron wave, persistently high mortality in specific high-risk groups underscores the importance of prioritizing booster vaccinations and intensified treatment for vulnera...

» Recommended immunizations to reduce respiratory morbidity and mortality among US adults with asthma, by age
08/05/25 20:00 from coronavirus
No abstract

» Impact of COVID-19 vaccination on symptoms and immune phenotypes in vaccine-naïve individuals with Long COVID
08/05/25 20:00 from sars-cov-2 spike protein
CONCLUSIONS: In this study of 16 people with Long COVID, vaccination is associated with increased SARS-CoV-2 spike protein-specific IgG and T cell expansion in most participants. Specific immune features are associated with symptom chang...

» Evolution of COVID-19 mortality risk: A retrospective study of three epidemic waves in Faridabad, India
08/05/25 20:00 from coronavirus
CONCLUSIONS: Understanding the shifting risk factors across COVID-19 epidemic waves is crucial for targeted interventions. Prioritizing high-risk groups, particularly during peak waves, can optimize resource allocation and minimize morta...

» Systematic review and meta-analysis of no show or non-attendance rates among telehealth and in-person models of care
08/05/25 20:00 from SARS-CoV-2 and Sars-Cov comparisons
CONCLUSIONS: The meta-analysis indicated that on average, telehealth models of care implemented since COVID-19 provide a moderate reduction in risk of patient non-attendance when compared to in-person alternatives.

» Thiol esters as chemical warheads of SARS-CoV-2 main protease (3CLpro) peptide-like inhibitors
08/05/25 20:00 from coronavirus
Peptide-like 3CLpro covalent binding inhibitors are the most effective antiviral drugs for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Their covalent warheads were designed based on the addition reaction activ...

» An overview of reviews on digital health interventions during COVID- 19 era: insights and lessons for future pandemics
08/05/25 20:00 from covid-19
CONCLUSIONS: This study identifies both the strengths and weaknesses of the current digital health landscape. It emphasizes the transformative impact of digital health technologies during the COVID- 19 pandemic and provides a roadmap for...

» Computationally designed proteins mimic antibody immune evasion in viral evolution
08/05/25 20:00 from sars-cov-2
Recurrent waves of viral infection necessitate vaccines and therapeutics that remain effective against emerging viruses. Our ability to evaluate interventions is currently limited to assessments against past or circulating variants, whic...

» Virus inactivation and skin safety studies using far-UVC LEDs
08/05/25 20:00 from coronavirus
Reducing airborne disease transmission is a public health goal. Far-UVC light, defined as 200-235 nm, is a promising technology to inactivate viruses within occupied spaces. This work examines state of the art far-UVC emitting LEDs, with...

» Diagnostic biomarkers and immune infiltration profiles common to COVID-19, acute myocardial infarction and acute ischaemic stroke using bioinformatics methods and machine learning
08/05/25 20:00 from Cell entry mechanisms of SARS-CoV-2
CONCLUSION: We employed bioinformatics methods and machine learning to investigate common diagnostic biomarkers and immune infiltration characteristics of COVID-19, AMI and AIS. Functional and pathway analyses indicated that the co-DEGs ...

» New-onset anesthesia/paresthesia following the administration of COVID-19 vaccines in Quebec, Canada
08/05/25 20:00 from sars-cov-2
CONCLUSION: Symptoms of anesthesia/paresthesia are commonly reported following the administration of several vaccines, including those against COVID-19. In most instances, symptoms occur shortly after vaccination, have a limited impact o...

» Mercaptophenylboronic Acid-Mediated Nanozyme Immunochromatographic Assay for Simultaneous Detection of Respiratory Bacteria and Virus
08/05/25 20:00 from coronavirus
Rapid, sensitive, and accurate detection of respiratory pathogens is essential yet challenging. Here, this study presents a universal nanozyme immunochromatographic assay (ICA) that utilizes the broad binding capacity of 4-mercaptophenyl...

» Co-production in HIV research: a case study from the COVID-19 pandemic
08/05/25 20:00 from covid-19
CONCLUSION: Participatory research and co-production are increasingly common approaches to research. These approaches have impacts on all stakeholders involved including co-researchers, public involvement practitioners, academic research...

» Epitope mapping of SARS-CoV-2 Spike protein using naturally-acquired immune responses to develop monoclonal antibodies
08/05/25 20:00 from sars-cov-2 spike protein
COVID-19 vaccination strategies are already available almost worldwide. However, it is also crucial to develop new therapeutic approaches, especially for vulnerable populations that may not fully respond to vaccination, such as the immun...

» Differential reactivity of SARS-CoV-2 S-protein T-cell epitopes in vaccinated versus naturally infected individuals
08/05/25 20:00 from sars-cov-2 spike protein
CONCLUSION: This study provides insight into T-cell responses against the SARS-CoV-2 S-protein following vaccination and subsequent natural infection.

» Thiol esters as chemical warheads of SARS-CoV-2 main protease (3CLpro) peptide-like inhibitors
08/05/25 20:00 from sars-cov-2
Peptide-like 3CLpro covalent binding inhibitors are the most effective antiviral drugs for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Their covalent warheads were designed based on the addition reaction activ...

» SIRT5-mediated desuccinylation of the porcine deltacoronavirus M protein drives pexophagy to enhance viral proliferation
08/05/25 20:00 from coronavirus
Porcine deltacoronavirus (PDCoV) is an emerging enteropathogenic coronavirus capable of infecting various animal species, including humans. In this study, we explored the roles of sirtuins (SIRTs), a conserved family of protein deacylase...

» The TyphiNET data visualisation dashboard: unlocking Salmonella Typhi genomics data to support public health
08/05/25 20:00 from covid-19
CONCLUSIONS: The TyphiNET dashboard provides an interactive platform for accessing genome-derived data on pathogen variant frequencies to inform typhoid control and intervention strategies. The platform is extensible in terms of both dat...

» Engineered bacteria as an orally administered anti-viral treatment and immunization system
08/05/25 20:00 from sars-cov-2 spike protein
The emergence of new viral pathogens necessitates innovative antiviral therapies and vaccines. Traditional approaches, such as monoclonal antibodies and vaccines, are often hindered by resistance, limited effectiveness, and high costs. H...

» Primary Care Physical Therapy and Exercise Therapy for People with Persistent Complaints after a SARS-CoV-2 Infection: Secondary Analysis of the ParaCov Prospective Cohort Study
08/05/25 20:00 from sars-cov-2
CONCLUSION: Most patients achieved their treatment goals and demonstrated clinically important improvements on PSFS and 6MWT. This study provides information on the most important therapeutic goals and provides estimates for realistic tr...

» Precision public health after Covid-19: a scoping review
08/05/25 20:00 from covid-19
"Precision public health" (PPH) emerged in 2015 as a charismatic vision to revolutionize traditional public health with data-driven solutions to the world's most challenging public health problems. A central goal of PPH is to use populat...

» Contact tracing strategies for infectious diseases: A systematic literature review
08/05/25 20:00 from coronavirus
Contact tracing has been a crucial public health strategy for breaking infectious diseases chains of transmission. Although many resources exist for disease outbreak management none address the rationale of contact tracing. This comprehe...

» Influence of anti-Spike protein antibody levels on tocilizumab efficacy in hospitalized patients with severe COVID-19 pneumonia: a post-hoc analysis of the COVACTA trial
08/05/25 20:00 from sars-cov-2 spike protein
CONCLUSIONS: Our findings suggest that using IL-6 inhibitors in severe COVID-19 patients with low S-spike antibody titers may improve clinical outcomes.

» Waning of anti-SARS-CoV-2 antibodies after the first wave of the COVID-19 pandemic in 2020: A 12-month-evaluation in three population-based European studies
08/05/25 20:00 from sars-cov-2
CONCLUSION: From population-based cohorts, anti-S IgG levels remained stable during the first 4 months following SARS-CoV-2 infection. Most of the decay occurred afterward; nearly one-third of people seroreverted 6 and 12 months later. L...

» COVID-19 infection history as a risk factor for early pregnancy loss: results from the electronic health record-based Southeast Texas COVID and Pregnancy Cohort Study
08/05/25 20:00 from covid-19
CONCLUSIONS: COVID-19 both prior to and during pregnancy was identified as a risk factor for spontaneous abortion in this study sample. These findings highlight the importance of COVID-19 vaccination and post-COVID management for pregnan...

» COVIVA: Effect of transcutaneous auricular vagal nerve stimulation on fatigue-syndrome in patients with Long Covid - A placebo-controlled pilot study protocol
08/05/25 20:00 from coronavirus
BACKGROUND: Up to 80% of patients who develop coronavirus disease-2019 (Covid-19) infection subsequently experience long covid/post-covid syndrome. The World Health Organization (WHO) has estimated that >770 million patients have been in...

» Academic institution extensive, building-by-building wastewater-based surveillance platform for SARS-CoV-2 monitoring, clinical data correlation, and potential national proxy
08/05/25 20:00 from sars-cov-2
In this work, we report on the performance of an extensive, building-by-building wastewater surveillance platform deployed across 38 locations of the largest private university system in Mexico, spanning 19 of the 32 states, to detect SA...

» Indicators associated with job morale of physicians in low- and middle-income countries during the COVID- 19 pandemic: a systematic review and meta-analysis
08/05/25 20:00 from covid-19
CONCLUSIONS: The findings suggest that job morale among physicians working in middle-income countries was generally low during the COVID- 19 pandemic. However, due to substantial variation and limited methodological quality among the stu...

» Human Metapneumovirus: A Comprehensive Epidemiological Analysis of a Global Respiratory Threat
08/05/25 20:00 from coronavirus
Human metapneumovirus (HMPV) is a significant respiratory pathogen that contributes to acute respiratory infections, particularly in vulnerable populations such as children, the elderly, and immunocompromised individuals. Since its disco...

» Association of mental health, quality of life, and SARS-CoV-2 infection in individuals in need of care: Results from a multicentre registry study
08/05/25 20:00 from sars-cov-2
CONCLUSION: Depression and anxiety were significantly associated with reduced quality of life, irrespective of living environment or SARS-CoV-2 infection status, underscoring the need for targeted mental health interventions in older adu...

» Prognostic value of functional CT imaging in COVID-ARDS: a two-centre prospective observational study
08/05/25 20:00 from covid-19
CONCLUSIONS: Our data show that in addition to recruitment, the spatial distribution of specific volume change, a surrogate measure of regional lung ventilation, is associated with the risk of death in mechanically ventilated COVID-19 AR...

» Immune Responses Against SARS-CoV-2 in Previously SARS-CoV-2-Infected Individuals after Receiving a Single Dose of CoronaVac or ChAdOx-1 Vaccine
08/05/25 20:00 from coronavirus
CONCLUSION: In post-SARS-CoV-2 infection, ChAd vaccination induced a better antibody response, but the CoVac vaccine induced greater T-cell responses. Vaccination is valuable in boosting immunity, particularly against some VOCs, in indiv...

» Valuing and retaining the dental workforce: a mixed-methods exploration of workforce sustainability in the North East of England
08/05/25 20:00 from covid-19
CONCLUSION: Findings highlight critical systemic barriers that threaten workforce sustainability in NHS dentistry. Addressing career progression pathways, improving collaboration, reforming contracts, and enhancing professional support s...

» Child Organ Offer Process (cOOPS): Understanding Infectious Risk Assessment and Mitigation Strategies
08/05/25 20:00 from coronavirus
CONCLUSIONS: For many pediatric organ offer scenarios, agreement in donor acceptance was high; however, improved education based on currently available recommendations may enhance organ acceptance decision-making. The variability in mana...

» Epidemiological characteristics of respiratory tract infections during and after the pandemic of COVID-19 from 2021 - 2023 in Shenzhen, southern China
08/05/25 20:00 from covid-19
CONCLUSION: The removal of non-pharmaceutical interventions following the COVID-19 pandemic has significantly affected the epidemiological and seasonal patterns of certain respiratory pathogens in Shenzhen. These findings highlight the n...

» COVID-19 and the impact of physical activity on persistent symptoms
08/05/25 20:00 from coronavirus
INTRODUCTION: Physical activity is protective against chronic disease but whether activity is associated with persistent symptoms in non-hospitalized coronavirus disease 2019 (COVID-19) survivors is unknown. The purpose of the study was ...

» The impact of COVID-19-related anxiety on obstetric complications and mental health in quarantined pregnant women
08/05/25 20:00 from covid-19
CONCLUSION: COVID-19-related fear in quarantined pregnant women was associated with obstetric complications (e.g., care avoidance) and mental health disorders (e.g., sleep disturbances). Despite modest correlations, findings underscore t...

» Synthesis, molecular docking, and in vitro activity of a novel angiotensin-converting enzyme 2 inhibitor, LMS1007: a potential molecule in Covid-19 and cancer treatments
08/05/25 20:00 from coronavirus
Angiotensin-converting enzyme 2 (ACE2) is a validated commonly studied in the pathology of several diseases, including novel coronavirus and breast cancer. Herein, we report the synthesis, molecular docking, and validation of a novel ACE...

» Impact of COVID-19 vaccination on symptoms and immune phenotypes in vaccine-naive individuals with Long COVID
08/05/25 20:00 from covid-19
CONCLUSIONS: In this study of 16 people with Long COVID, vaccination is associated with increased SARS-CoV-2 spike protein-specific IgG and T cell expansion in most participants. Specific immune features are associated with symptom chang...

» COVID-19 conspiracy beliefs in Poland. Predictors, psychological and social impact and adherence to public health guidelines over one year
08/05/25 20:00 from covid-19
This study examines demographic and attitudinal determinants of belief in COVID-19 conspiracy beliefs in Poland and their impact on psychological well-being, social functioning, and adherence to public health measures over one year. A cr...

» Characterizing spatial epidemiology in a heterogeneous transmission landscape using the spatial transmission count statistic
08/05/25 20:00 from covid-19
CONCLUSIONS: In this study, we introduce the Source Sink Score, which determines whether a localized outbreak serves as a source or sink for other regions, and the Local Import Score, which assesses whether the outbreak has transitioned ...

» Epitope mapping of SARS-CoV-2 Spike protein using naturally-acquired immune responses to develop monoclonal antibodies
08/05/25 20:00 from covid-19
COVID-19 vaccination strategies are already available almost worldwide. However, it is also crucial to develop new therapeutic approaches, especially for vulnerable populations that may not fully respond to vaccination, such as the immun...

» COVID-19 infection history as a risk factor for early pregnancy loss: results from the electronic health record-based Southeast Texas COVID and Pregnancy Cohort Study
08/05/25 20:00 from sars-cov-2
CONCLUSIONS: COVID-19 both prior to and during pregnancy was identified as a risk factor for spontaneous abortion in this study sample. These findings highlight the importance of COVID-19 vaccination and post-COVID management for pregnan...

» Co-production in HIV research: a case study from the COVID-19 pandemic
08/05/25 20:00 from coronavirus
CONCLUSION: Participatory research and co-production are increasingly common approaches to research. These approaches have impacts on all stakeholders involved including co-researchers, public involvement practitioners, academic research...

» Prognostic value of functional CT imaging in COVID-ARDS: a two-centre prospective observational study
08/05/25 20:00 from sars-cov-2
CONCLUSIONS: Our data show that in addition to recruitment, the spatial distribution of specific volume change, a surrogate measure of regional lung ventilation, is associated with the risk of death in mechanically ventilated COVID-19 AR...

» The TyphiNET data visualisation dashboard: unlocking Salmonella Typhi genomics data to support public health
08/05/25 20:00 from coronavirus
CONCLUSIONS: The TyphiNET dashboard provides an interactive platform for accessing genome-derived data on pathogen variant frequencies to inform typhoid control and intervention strategies. The platform is extensible in terms of both dat...

» Impact of COVID-19 vaccination on symptoms and immune phenotypes in vaccine-naïve individuals with Long COVID
08/05/25 20:00 from sars-cov-2
CONCLUSIONS: In this study of 16 people with Long COVID, vaccination is associated with increased SARS-CoV-2 spike protein-specific IgG and T cell expansion in most participants. Specific immune features are associated with symptom chang...

» Recommended immunizations to reduce respiratory morbidity and mortality among US adults with asthma, by age
08/05/25 20:00 from coronavirus
No abstract

» Characterizing spatial epidemiology in a heterogeneous transmission landscape using the spatial transmission count statistic
08/05/25 20:00 from sars-cov-2
CONCLUSIONS: In this study, we introduce the Source Sink Score, which determines whether a localized outbreak serves as a source or sink for other regions, and the Local Import Score, which assesses whether the outbreak has transitioned ...

» Evolution of COVID-19 mortality risk: A retrospective study of three epidemic waves in Faridabad, India
08/05/25 20:00 from coronavirus
CONCLUSIONS: Understanding the shifting risk factors across COVID-19 epidemic waves is crucial for targeted interventions. Prioritizing high-risk groups, particularly during peak waves, can optimize resource allocation and minimize morta...

» Epitope mapping of SARS-CoV-2 Spike protein using naturally-acquired immune responses to develop monoclonal antibodies
08/05/25 20:00 from sars-cov-2
COVID-19 vaccination strategies are already available almost worldwide. However, it is also crucial to develop new therapeutic approaches, especially for vulnerable populations that may not fully respond to vaccination, such as the immun...

» Thiol esters as chemical warheads of SARS-CoV-2 main protease (3CLpro) peptide-like inhibitors
08/05/25 20:00 from coronavirus
Peptide-like 3CLpro covalent binding inhibitors are the most effective antiviral drugs for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Their covalent warheads were designed based on the addition reaction activ...

» Tubulointerstitial nephritis and uveitis post COVID-19 infection in an adult
08/05/25 20:00 from sars-cov-2
A woman in her 50s contracted COVID-19 and initially presented a few weeks afterwards with left eye pain and redness. She was diagnosed with uveitis and treated with glucocorticoid eye drops. Renal impairment was found on laboratory inve...

» Virus inactivation and skin safety studies using far-UVC LEDs
08/05/25 20:00 from coronavirus
Reducing airborne disease transmission is a public health goal. Far-UVC light, defined as 200-235 nm, is a promising technology to inactivate viruses within occupied spaces. This work examines state of the art far-UVC emitting LEDs, with...

» Efficacy of initial combination therapy with anti-SARS-CoV-2 antivirals targeting viral clearance in COVID-19 patients with B-cell lymphoma treated with anti-CD20 antibodies: A retrospective single-centre study in Japan
08/05/25 20:00 from sars-cov-2
CONCLUSION: This study showed the potential of early combination antiviral therapy to shorten the time to viral clearance in this high-risk patient population.

» Mercaptophenylboronic Acid-Mediated Nanozyme Immunochromatographic Assay for Simultaneous Detection of Respiratory Bacteria and Virus
08/05/25 20:00 from coronavirus
Rapid, sensitive, and accurate detection of respiratory pathogens is essential yet challenging. Here, this study presents a universal nanozyme immunochromatographic assay (ICA) that utilizes the broad binding capacity of 4-mercaptophenyl...

» In-hospital Mortality Among Children and Adults Hospitalized with COVID-19 in Africa Across Pre-Delta, Delta, and Omicron SARS-CoV-2 Waves
08/05/25 20:00 from sars-cov-2
CONCLUSION: Despite a general reduction in mortality risk during Omicron wave, persistently high mortality in specific high-risk groups underscores the importance of prioritizing booster vaccinations and intensified treatment for vulnera...

» SIRT5-mediated desuccinylation of the porcine deltacoronavirus M protein drives pexophagy to enhance viral proliferation
08/05/25 20:00 from coronavirus
Porcine deltacoronavirus (PDCoV) is an emerging enteropathogenic coronavirus capable of infecting various animal species, including humans. In this study, we explored the roles of sirtuins (SIRTs), a conserved family of protein deacylase...

» Computationally designed proteins mimic antibody immune evasion in viral evolution
08/05/25 20:00 from sars-cov-2
Recurrent waves of viral infection necessitate vaccines and therapeutics that remain effective against emerging viruses. Our ability to evaluate interventions is currently limited to assessments against past or circulating variants, whic...

» Contact tracing strategies for infectious diseases: A systematic literature review
08/05/25 20:00 from coronavirus
Contact tracing has been a crucial public health strategy for breaking infectious diseases chains of transmission. Although many resources exist for disease outbreak management none address the rationale of contact tracing. This comprehe...

» New-onset anesthesia/paresthesia following the administration of COVID-19 vaccines in Quebec, Canada
08/05/25 20:00 from sars-cov-2
CONCLUSION: Symptoms of anesthesia/paresthesia are commonly reported following the administration of several vaccines, including those against COVID-19. In most instances, symptoms occur shortly after vaccination, have a limited impact o...

» COVIVA: Effect of transcutaneous auricular vagal nerve stimulation on fatigue-syndrome in patients with Long Covid - A placebo-controlled pilot study protocol
08/05/25 20:00 from coronavirus
BACKGROUND: Up to 80% of patients who develop coronavirus disease-2019 (Covid-19) infection subsequently experience long covid/post-covid syndrome. The World Health Organization (WHO) has estimated that >770 million patients have been in...

» Cultural practices, healthcare-seeking behaviors, and wildlife interface: Zoonotic disease risks among the Phu Thai Ethnic Group in Thailand
08/05/25 20:00 from Coronavirus origins
CONCLUSION: This study highlights the complex interplay between culture, healthcare access, and zoonotic risks in the Phu Thai community. Enhancing culturally sensitive health education, promoting safe wildlife interaction practices, and...

» Thiol esters as chemical warheads of SARS-CoV-2 main protease (3CLpro) peptide-like inhibitors
08/05/25 20:00 from sars-cov-2
Peptide-like 3CLpro covalent binding inhibitors are the most effective antiviral drugs for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Their covalent warheads were designed based on the addition reaction activ...

» Human Metapneumovirus: A Comprehensive Epidemiological Analysis of a Global Respiratory Threat
08/05/25 20:00 from coronavirus
Human metapneumovirus (HMPV) is a significant respiratory pathogen that contributes to acute respiratory infections, particularly in vulnerable populations such as children, the elderly, and immunocompromised individuals. Since its disco...

» Immune Responses Against SARS-CoV-2 in Previously SARS-CoV-2-Infected Individuals after Receiving a Single Dose of CoronaVac or ChAdOx-1 Vaccine
08/05/25 20:00 from coronavirus
CONCLUSION: In post-SARS-CoV-2 infection, ChAd vaccination induced a better antibody response, but the CoVac vaccine induced greater T-cell responses. Vaccination is valuable in boosting immunity, particularly against some VOCs, in indiv...

» Primary Care Physical Therapy and Exercise Therapy for People with Persistent Complaints after a SARS-CoV-2 Infection: Secondary Analysis of the ParaCov Prospective Cohort Study
08/05/25 20:00 from sars-cov-2
CONCLUSION: Most patients achieved their treatment goals and demonstrated clinically important improvements on PSFS and 6MWT. This study provides information on the most important therapeutic goals and provides estimates for realistic tr...

» Child Organ Offer Process (cOOPS): Understanding Infectious Risk Assessment and Mitigation Strategies
08/05/25 20:00 from coronavirus
CONCLUSIONS: For many pediatric organ offer scenarios, agreement in donor acceptance was high; however, improved education based on currently available recommendations may enhance organ acceptance decision-making. The variability in mana...

» Waning of anti-SARS-CoV-2 antibodies after the first wave of the COVID-19 pandemic in 2020: A 12-month-evaluation in three population-based European studies
08/05/25 20:00 from sars-cov-2
CONCLUSION: From population-based cohorts, anti-S IgG levels remained stable during the first 4 months following SARS-CoV-2 infection. Most of the decay occurred afterward; nearly one-third of people seroreverted 6 and 12 months later. L...

» COVID-19 and the impact of physical activity on persistent symptoms
08/05/25 20:00 from coronavirus
INTRODUCTION: Physical activity is protective against chronic disease but whether activity is associated with persistent symptoms in non-hospitalized coronavirus disease 2019 (COVID-19) survivors is unknown. The purpose of the study was ...

» Academic institution extensive, building-by-building wastewater-based surveillance platform for SARS-CoV-2 monitoring, clinical data correlation, and potential national proxy
08/05/25 20:00 from sars-cov-2
In this work, we report on the performance of an extensive, building-by-building wastewater surveillance platform deployed across 38 locations of the largest private university system in Mexico, spanning 19 of the 32 states, to detect SA...

» Synthesis, molecular docking, and in vitro activity of a novel angiotensin-converting enzyme 2 inhibitor, LMS1007: a potential molecule in Covid-19 and cancer treatments
08/05/25 20:00 from coronavirus
Angiotensin-converting enzyme 2 (ACE2) is a validated commonly studied in the pathology of several diseases, including novel coronavirus and breast cancer. Herein, we report the synthesis, molecular docking, and validation of a novel ACE...

» Association of mental health, quality of life, and SARS-CoV-2 infection in individuals in need of care: Results from a multicentre registry study
08/05/25 20:00 from sars-cov-2
CONCLUSION: Depression and anxiety were significantly associated with reduced quality of life, irrespective of living environment or SARS-CoV-2 infection status, underscoring the need for targeted mental health interventions in older adu...

» Cultural practices, healthcare-seeking behaviors, and wildlife interface: Zoonotic disease risks among the Phu Thai Ethnic Group in Thailand
08/05/25 20:00 from Covid-19 origins
CONCLUSION: This study highlights the complex interplay between culture, healthcare access, and zoonotic risks in the Phu Thai community. Enhancing culturally sensitive health education, promoting safe wildlife interaction practices, and...

» Systematic review and meta-analysis of no show or non-attendance rates among telehealth and in-person models of care
08/05/25 20:00 from SARS-CoV-2 and Sars-Cov comparisons
CONCLUSIONS: The meta-analysis indicated that on average, telehealth models of care implemented since COVID-19 provide a moderate reduction in risk of patient non-attendance when compared to in-person alternatives.

» Evaluation of biofilm formation, antimicrobial pattern, and typing of Stenotrophomonas maltophilia isolated from clinical sources in Brazil
08/05/25 20:00 from Covid-19 origins
This study aimed to evaluate the biofilm formation and disinfectant tolerance of Stenotrophomonas maltophilia strains originated from hospitalized patients during the COVID-19 pandemic. Nine strains were isolated from different clinical ...

» Diagnostic biomarkers and immune infiltration profiles common to COVID-19, acute myocardial infarction and acute ischaemic stroke using bioinformatics methods and machine learning
08/05/25 20:00 from Cell entry mechanisms of SARS-CoV-2
CONCLUSION: We employed bioinformatics methods and machine learning to investigate common diagnostic biomarkers and immune infiltration characteristics of COVID-19, AMI and AIS. Functional and pathway analyses indicated that the co-DEGs ...

» Impact of COVID-19 vaccination on symptoms and immune phenotypes in vaccine-naïve individuals with Long COVID
08/05/25 20:00 from sars-cov-2 spike protein
CONCLUSIONS: In this study of 16 people with Long COVID, vaccination is associated with increased SARS-CoV-2 spike protein-specific IgG and T cell expansion in most participants. Specific immune features are associated with symptom chang...

» The Nexus between music classes and psychological wellbeing: the moderating role of sustainable education policy and teachers innovative support in the post Covid-19 era
08/05/25 20:00 from covid-19
PURPOSE: The study was conducted to address the gaps in literature and improve the psychological well-being of Chinese students. For this purpose, the impact of music classes on psychological well-being of the students was investigated. ...

» An overview of reviews on digital health interventions during COVID- 19 era: insights and lessons for future pandemics
08/05/25 20:00 from covid-19
CONCLUSIONS: This study identifies both the strengths and weaknesses of the current digital health landscape. It emphasizes the transformative impact of digital health technologies during the COVID- 19 pandemic and provides a roadmap for...

» Epitope mapping of SARS-CoV-2 Spike protein using naturally-acquired immune responses to develop monoclonal antibodies
08/05/25 20:00 from sars-cov-2 spike protein
COVID-19 vaccination strategies are already available almost worldwide. However, it is also crucial to develop new therapeutic approaches, especially for vulnerable populations that may not fully respond to vaccination, such as the immun...

» Differential reactivity of SARS-CoV-2 S-protein T-cell epitopes in vaccinated versus naturally infected individuals
08/05/25 20:00 from sars-cov-2 spike protein
CONCLUSION: This study provides insight into T-cell responses against the SARS-CoV-2 S-protein following vaccination and subsequent natural infection.

» Co-production in HIV research: a case study from the COVID-19 pandemic
08/05/25 20:00 from covid-19
CONCLUSION: Participatory research and co-production are increasingly common approaches to research. These approaches have impacts on all stakeholders involved including co-researchers, public involvement practitioners, academic research...

» The TyphiNET data visualisation dashboard: unlocking Salmonella Typhi genomics data to support public health
08/05/25 20:00 from covid-19
CONCLUSIONS: The TyphiNET dashboard provides an interactive platform for accessing genome-derived data on pathogen variant frequencies to inform typhoid control and intervention strategies. The platform is extensible in terms of both dat...

» Engineered bacteria as an orally administered anti-viral treatment and immunization system
08/05/25 20:00 from sars-cov-2 spike protein
The emergence of new viral pathogens necessitates innovative antiviral therapies and vaccines. Traditional approaches, such as monoclonal antibodies and vaccines, are often hindered by resistance, limited effectiveness, and high costs. H...

» Precision public health after Covid-19: a scoping review
08/05/25 20:00 from covid-19
"Precision public health" (PPH) emerged in 2015 as a charismatic vision to revolutionize traditional public health with data-driven solutions to the world's most challenging public health problems. A central goal of PPH is to use populat...

» Influence of anti-Spike protein antibody levels on tocilizumab efficacy in hospitalized patients with severe COVID-19 pneumonia: a post-hoc analysis of the COVACTA trial
08/05/25 20:00 from sars-cov-2 spike protein
CONCLUSIONS: Our findings suggest that using IL-6 inhibitors in severe COVID-19 patients with low S-spike antibody titers may improve clinical outcomes.

» COVID-19 infection history as a risk factor for early pregnancy loss: results from the electronic health record-based Southeast Texas COVID and Pregnancy Cohort Study
08/05/25 20:00 from covid-19
CONCLUSIONS: COVID-19 both prior to and during pregnancy was identified as a risk factor for spontaneous abortion in this study sample. These findings highlight the importance of COVID-19 vaccination and post-COVID management for pregnan...

» Indicators associated with job morale of physicians in low- and middle-income countries during the COVID- 19 pandemic: a systematic review and meta-analysis
08/05/25 20:00 from covid-19
CONCLUSIONS: The findings suggest that job morale among physicians working in middle-income countries was generally low during the COVID- 19 pandemic. However, due to substantial variation and limited methodological quality among the stu...

» Prognostic value of functional CT imaging in COVID-ARDS: a two-centre prospective observational study
08/05/25 20:00 from covid-19
CONCLUSIONS: Our data show that in addition to recruitment, the spatial distribution of specific volume change, a surrogate measure of regional lung ventilation, is associated with the risk of death in mechanically ventilated COVID-19 AR...

» Valuing and retaining the dental workforce: a mixed-methods exploration of workforce sustainability in the North East of England
08/05/25 20:00 from covid-19
CONCLUSION: Findings highlight critical systemic barriers that threaten workforce sustainability in NHS dentistry. Addressing career progression pathways, improving collaboration, reforming contracts, and enhancing professional support s...

» Epidemiological characteristics of respiratory tract infections during and after the pandemic of COVID-19 from 2021 - 2023 in Shenzhen, southern China
08/05/25 20:00 from covid-19
CONCLUSION: The removal of non-pharmaceutical interventions following the COVID-19 pandemic has significantly affected the epidemiological and seasonal patterns of certain respiratory pathogens in Shenzhen. These findings highlight the n...

» The impact of COVID-19-related anxiety on obstetric complications and mental health in quarantined pregnant women
08/05/25 20:00 from covid-19
CONCLUSION: COVID-19-related fear in quarantined pregnant women was associated with obstetric complications (e.g., care avoidance) and mental health disorders (e.g., sleep disturbances). Despite modest correlations, findings underscore t...

» Impact of COVID-19 vaccination on symptoms and immune phenotypes in vaccine-naive individuals with Long COVID
08/05/25 20:00 from covid-19
CONCLUSIONS: In this study of 16 people with Long COVID, vaccination is associated with increased SARS-CoV-2 spike protein-specific IgG and T cell expansion in most participants. Specific immune features are associated with symptom chang...

» COVID-19 conspiracy beliefs in Poland. Predictors, psychological and social impact and adherence to public health guidelines over one year
08/05/25 20:00 from covid-19
This study examines demographic and attitudinal determinants of belief in COVID-19 conspiracy beliefs in Poland and their impact on psychological well-being, social functioning, and adherence to public health measures over one year. A cr...

» Characterizing spatial epidemiology in a heterogeneous transmission landscape using the spatial transmission count statistic
08/05/25 20:00 from covid-19
CONCLUSIONS: In this study, we introduce the Source Sink Score, which determines whether a localized outbreak serves as a source or sink for other regions, and the Local Import Score, which assesses whether the outbreak has transitioned ...

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